Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720835 | 0.89 | ACACB (0.64) | ACACBMTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL3726818 | 0.89 | ACACB (0.64) | ACACBMTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL3722470 | 0.88 | MAPT (0.51) | ACACBMTNR1AMAPTLMNAHTT | |
| SCHEMBL3723896 | 0.86 | GLA (0.59) | ACACBMAPTLMNAHTTNPC1 | |
| SCHEMBL10188629 | 0.81 | ACACB (0.80) | ACACBMTNR1AMAPTLMNANPC1 | |
| SCHEMBL9493169 | 0.81 | MTNR1A (0.60) | MTNR1AMTNR1BMAPTLMNANPC1 | |
| SCHEMBL3720307 | 0.81 | MTNR1A (0.61) | ACACBMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL165793 | 0.79 | ACACB (1.00) | ACACBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3716760 | 0.79 | KMT2A (0.55) | ACACBMTNR1AMAPTLMNANPC1 | |
| SCHEMBL13652571 | 0.78 | MTNR1A (0.62) | ACACBMTNR1AMTNR1BMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |