Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.61 |
| ▸ | ACACB | O00763 | 3/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.50 |
| ▸ | ACACA | Q13085 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726818 | 0.91 | ACACB (0.64) | MTNR1AACACBMTNR1BSMN1; SMN2 | |
| SCHEMBL3724114 | 0.88 | SMN1; SMN2 (0.62) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL3720876 | 0.87 | MTNR1A (0.53) | MTNR1AACACBMTNR1BSMN1; SMN2 | |
| SCHEMBL3726746 | 0.84 | ACACB (0.53) | MTNR1AACACBMTNR1BSMN1; SMN2 | |
| SCHEMBL3719870 | 0.84 | LTA4H (0.53) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL3720261 | 0.83 | ACACB (0.51) | MTNR1AACACBMTNR1BSMN1; SMN2 | |
| SCHEMBL3724679 | 0.83 | ACACB (0.51) | MTNR1AACACBMTNR1BSMN1; SMN2 | |
| SCHEMBL3722415 | 0.83 | ACACB (0.51) | MTNR1AACACBMTNR1BSMN1; SMN2 | |
| SCHEMBL3724593 | 0.83 | ACACB (0.59) | MTNR1AACACBMTNR1BACACASMN1; SMN2 | |
| SCHEMBL3726453 | 0.81 | KDM4E (0.63) | MTNR1AACACBMTNR1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |