Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458715 | 0.89 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTHSD17B10HTT | |
| SCHEMBL30091844 | 0.84 | NPC1 (0.57) | GAAMAPTHTTLMNARAB9A | |
| SCHEMBL10953163 | 0.83 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL29277127 | 0.83 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTHSD17B10HTT | |
| SCHEMBL28462916 | 0.82 | KMT2A (0.59) | ALDH1A1GAAMAPTHSD17B10LMNA | |
| SCHEMBL11776107 | 0.81 | TSHR (0.56) | ALDH1A1GAAMAPTHSD17B10HTT | |
| SCHEMBL28804225 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL27776272 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL29728552 | 0.80 | KMT2A (0.52) | ALDH1A1KDM4EMAPTHSD17B10HTT | |
| SCHEMBL7029967 | 0.80 | KMT2A (0.52) | ALDH1A1KDM4EMAPTHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120994-A2 | UREIDOARYL-AND CARBAMOYLARYL-MORPHOLINO- PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESIS | WYETH LLC (US) | 2010-10-21 | — | — | WO | disclosed |
| US-4507445-A | Heat-curable epoxide resin compositions | CIBA-GEIGY CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| US-4378318-A | HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-03-29 | — | — | US | disclosed |