SCHEMBL7029967

SCHEMBL7029967

NC(=O)Oc1ccccc1OC(N)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
CTNNB1 P35222 1/20 0.43
SERPINE1 P05121 1/20 0.43
IRAK4 Q9NWZ3 1/20 0.42
MAPT P10636 3/20 0.42
HSD17B10 Q99714 3/20 0.42
TSHR P16473 2/20 0.42
BLM P54132 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
POLB P06746 2/20 0.42
CYP3A4 P08684 1/20 0.42
PARP1 P09874 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
PMP22 Q01453 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PRSS1 P07477 1/20 0.42
ACR P10323 1/20 0.42
CA12 O43570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728552 1.00 KMT2A (0.52) KMT2AMEN1CTNNB1SERPINE1IRAK4
SCHEMBL3952526 0.91 CA1 (0.59) KMT2AMAPTTSHRTDP1POLB
SCHEMBL26566772 0.89 PTGS2 (0.57) KMT2AMEN1HSD17B10TSHRBLM
SCHEMBL29728528 0.87 KMT2A (0.46) KMT2AMEN1CTNNB1IRAK4MAPT
SCHEMBL142738 0.85 SMN1; SMN2 (0.49) KMT2AMEN1CTNNB1IRAK4MAPT
SCHEMBL29463214 0.85 GAA (0.50) KMT2AMEN1CTNNB1SERPINE1MAPT
SCHEMBL140239 0.85 GAA (0.50) KMT2AMEN1CTNNB1SERPINE1MAPT
SCHEMBL32677395 0.85 SMN1; SMN2 (0.49) KMT2AMEN1CTNNB1IRAK4MAPT
SCHEMBL32677394 0.85 SMN1; SMN2 (0.49) KMT2AMEN1CTNNB1IRAK4MAPT
SCHEMBL9629071 0.85 CTNNB1 (0.61) KMT2AMEN1CTNNB1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1284992-A2 POLYUBIQUITIN BASED HYDROGEL AND USES THEREOF Viridis Biotech Inc. (CA) 2003-02-26 EP claimed
WO-2001091814-A2 POLYUBIQUITIN BASED HYDROGEL AND USES THEREOF VIRIDIS BIOTECH INC. (CA) 2001-12-06 WO claimed
EP-0748157-B1 METHOD FOR PRODUCING PESTICIDE COMPOSITION HOECHST SCHERING AGREVO GMBH (DE) 1999-10-20 EP claimed
US-5747417-A CARBAMOYLOXYPHENYL CARBAMATE HERBICIDE, OIL-IN-WATER EMULSION HOECHST SCHERING AGREVO GMBH (DE) 1998-05-05 US claimed
EP-0748157-A1 METHOD FOR PRODUCING PESTICIDE COMPOSITION Hoechst Schering AgrEvo GmbH (DE) 1996-12-18 EP claimed
WO-1996037101-A1 HERBICIDE FORMULATIONS AND METHODS FOR THEIR PREPARATION KEMIRA AGRO OY (FI) 1996-11-28 WO claimed
WO-1995023505-A1 METHOD FOR PRODUCING PESTICIDE COMPOSITION KEMIRA AGRO OY (FI) 1995-09-08 WO claimed
US-10189777-B2 Benzenesulfonamido and related compounds for use as agonists of RORγ and the treatment of disease LYCERA CORPORATION (US) 2019-01-29 US disclosed
EP-3209641-A2 BENZENESULFONAMIDO AND RELATED COMPOUNDS FOR USE AS AGONISTS OF ROR AND THE TREATEMENT OF DISEASE Lycera Corporation (US) 2017-08-30 EP disclosed
US-20170190659-A1 BENZENESULFONAMIDO AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE WILMINGTON TRUST, NATIONAL ASSOCIATION 2017-07-06 US disclosed
EP-0748157-B1 METHOD FOR PRODUCING PESTICIDE COMPOSITION HOECHST SCHERING AGREVO GMBH (DE) 1999-10-20 EP disclosed
US-5747417-A CARBAMOYLOXYPHENYL CARBAMATE HERBICIDE, OIL-IN-WATER EMULSION HOECHST SCHERING AGREVO GMBH (DE) 1998-05-05 US disclosed
EP-0748157-A1 METHOD FOR PRODUCING PESTICIDE COMPOSITION Hoechst Schering AgrEvo GmbH (DE) 1996-12-18 EP disclosed
WO-1996037101-A1 HERBICIDE FORMULATIONS AND METHODS FOR THEIR PREPARATION KEMIRA AGRO OY (FI) 1996-11-28 WO disclosed
WO-1996037101-A1 HERBICIDE FORMULATIONS AND METHODS FOR THEIR PREPARATION KEMIRA AGRO OY (FI) 1996-11-28 WO disclosed
WO-1995023505-A1 METHOD FOR PRODUCING PESTICIDE COMPOSITION KEMIRA AGRO OY (FI) 1995-09-08 WO disclosed
EP-0201417-A1 Surfactant composition, process for its preparation and its use RHONE-POULENC CHIMIE (FR) 1986-11-12 EP disclosed
EP-0197250-A2 Herbicidal compositions based on carbomoyloxy phenyl carbamates and mineral petroleum oil ATOCHEM AGRI S.A. (FR) 1986-10-15 EP disclosed
EP-0197250-A2 Herbicidal compositions based on carbomoyloxy phenyl carbamates and mineral petroleum oil ATOCHEM AGRI S.A. (FR) 1986-10-15 EP disclosed
US-3869275-A HERBICIDAL MIXTURES SCHERING AG 1975-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189777-B2 Benzenesulfonamido and related compounds for use as agonists of RORγ and the treatment of disease RORC, RORB, RORA KMT2A 2706/4885MEN1 4353/4885CTNNB1 490/4885
US-20170190659-A1 BENZENESULFONAMIDO AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE RORB, RORA, RORC KMT2A 2458/4885MEN1 3902/4885CTNNB1 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.