Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL3726945

CCOC(CC(=O)O)C(=O)O.OCCOCCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.40
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
THRB P10828 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.36
PPARA Q07869 10/20 0.36
PPARG P37231 6/20 0.34
PPARD Q03181 3/20 0.34
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3729359 0.89 PPARA (0.39) PPARAPPARGPPARDTDP1
Di(Hydroxyethyl)Ether SCHEMBL3730783 0.88 TSHR (0.44) TSHRALDH1A1MEN1KMT2ATHRB
SCHEMBL16407998 0.87 PPARA (0.42) PPARAPPARGPPARDTDP1
SCHEMBL2185057 0.87 PPARA (0.42) PPARAPPARGPPARDTDP1
SCHEMBL9774225 0.85 MEN1 (0.42) TSHRMEN1KMT2ATHRBHTT
1,4-Butanediol SCHEMBL3738776 0.85 PPARA (0.37) PPARAPPARGPPARDCYP4F2CYP4A11
Di(Hydroxyethyl)Ether SCHEMBL3742578 0.85 TSHR (0.55) TSHRALDH1A1MEN1KMT2ATHRB
Tetraethylene Glycol SCHEMBL3746402 0.83 TSHR (0.53) TSHRALDH1A1MEN1KMT2ATHRB
Triethylene Glycol SCHEMBL3736941 0.83 TSHR (0.53) TSHRALDH1A1MEN1KMT2ATHRB
Di(Hydroxyethyl)Ether SCHEMBL3731296 0.81 TSHR (0.39) TSHRALDH1A1MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825178-B2 Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-02 US disclosed
US-20070289481-A1 Leveling Agent for Floor Polish and Aqueous Floor Polish Composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed