Ethylene Glycol

Ethylene Glycol

SCHEMBL3729359

CCOC(CC(=O)O)C(=O)O.OCCO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 13/20 0.39
TDP1 Q9NUW8 1/20 0.36
PPARG P37231 8/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
PPARD Q03181 6/20 0.34
FFAR1 O14842 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2185057 0.94 PPARA (0.42) PPARATDP1PPARGSMN1; SMN2PPARD
SCHEMBL16407998 0.94 PPARA (0.42) PPARATDP1PPARGSMN1; SMN2PPARD
1,4-Butanediol SCHEMBL3738776 0.92 PPARA (0.37) PPARATDP1PPARGSMN1; SMN2PPARD
Di(Hydroxyethyl)Ether SCHEMBL3726945 0.89 TSHR (0.41) PPARATDP1PPARGPPARD
Propylene Glycol SCHEMBL3729121 0.86 TDP1 (0.37) PPARATDP1PPARGSMN1; SMN2PPARD
Ethylene Glycol SCHEMBL3731973 0.84 CYP2C19 (0.34) TDP1SMN1; SMN2SLC22A6
Aspartic Acid SCHEMBL23794557 0.82 GRIK1 (0.44) PPARA
Methane SCHEMBL28916238 0.82 PPARA (0.36) PPARATDP1PPARGSMN1; SMN2PPARD
Ethylene Glycol SCHEMBL3732513 0.81 TSHR (0.41)
Ethylene Glycol SCHEMBL3731034 0.78 TDP1 (0.39) PPARATDP1PPARGSMN1; SMN2PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825178-B2 Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-02 US disclosed
US-20070289481-A1 Leveling Agent for Floor Polish and Aqueous Floor Polish Composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed