Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 5/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | RNMT | O43148 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18787574 | 0.95 | TYMP (0.42) | TYMPADORA1ADORA3ADORA2BPRKAG1 | |
| SCHEMBL1327824 | 0.94 | TYMP (0.40) | TYMPADORA1ADORA3ADORA2BPRKAG1 | |
| SCHEMBL29581997 | 0.93 | TYMP (0.43) | TYMPADORA1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL26535891 | 0.93 | TYMP (0.43) | TYMPADORA1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL668595 | 0.93 | TYMP (0.43) | TYMPADORA1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL24878603 | 0.93 | TYMP (0.43) | TYMPADORA1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL25873876 | 0.93 | TYMP (0.43) | TYMPADORA1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL12765877 | 0.92 | TYMP (0.39) | TYMPADORA1ADORA3ADORA2BPRKAG1 | |
| SCHEMBL22787289 | 0.91 | TYMP (0.42) | TYMPADORA1ADORA3ADORA2BPRKAG1 | |
| SCHEMBL2258922 | 0.91 | TYMP (0.43) | TYMPADORA1PRKAG1PRKAA1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280098-A1 | RECEPTOR TARGETED OLIGONUCLEOTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-11-04 | — | — | US | disclosed |