Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634657 | 0.92 | KIF11 (0.55) | KIF11 | |
| SCHEMBL34052 | 0.92 | KIF11 (0.55) | KIF11 | |
| SCHEMBL8447104 | 0.92 | KIF11 (0.55) | KIF11 | |
| SCHEMBL974722 | 0.87 | KIF11 (0.63) | KIF11 | |
| SCHEMBL7803198 | 0.85 | KIF11 (0.68) | KIF11 | |
| SCHEMBL17493268 | 0.79 | KIF11 (0.43) | KIF11 | |
| SCHEMBL7803196 | 0.79 | KIF11 (0.44) | KIF11 | |
| SCHEMBL6762948 | 0.79 | KIF11 (0.59) | KIF11 | |
| SCHEMBL13124532 | 0.79 | KIF11 (0.64) | KIF11 | |
| SCHEMBL19371248 | 0.79 | KIF11 (0.77) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562931-B2 | Process for the preparation of (1S, 4S, 7Z, 10S, 16E, 21R)-7-ethyldene-4,21-bis(1-methyl-ethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3, 6, 9, 19, 22-pentone | MSN LABORATORIES PRIVATE LIMITED (IN) | 2020-02-18 | — | — | US | disclosed |
| US-20180312538-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (1S, 4S, 7Z, 10S, 16E, 21R)-7-ETHYLDENE-4,21-BIS(1-METHYL-ETHYL)-2-OXA-12,13-DITHIA-5,8,20,23-TETRAAZABICYCLO [8.7.6]TRICOS-16-ENE-3, 6, 9, 19, 22-PENTONE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2018-11-01 | — | — | US | disclosed |
| WO-2017068596-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (1S, 4S, 7Z, 10S, 16E, 21R)- 7-ETHYLIDENE-4,21-BIS(1-METHYLETHYL)-2-OXA-12,13-DITHIA-5, 8, 20, 23- TETRAAZABICYCLO[8.7.6]TRICOS-16-ENE-3, 6, 9, 19, 22-PENTONE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2017-04-27 | — | — | WO | disclosed |
| WO-2017068596-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (1S, 4S, 7Z, 10S, 16E, 21R)- 7-ETHYLIDENE-4,21-BIS(1-METHYLETHYL)-2-OXA-12,13-DITHIA-5, 8, 20, 23- TETRAAZABICYCLO[8.7.6]TRICOS-16-ENE-3, 6, 9, 19, 22-PENTONE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2017-04-27 | — | — | WO | disclosed |
| US-9200104-B2 | Polymer | WARWICK EFFECT POLYMERS LIMITED (GB) | 2015-12-01 | — | — | US | disclosed |
| US-9200104-B2 | Polymer | WARWICK EFFECT POLYMERS LIMITED (GB) | 2015-12-01 | — | — | US | disclosed |
| US-20130295040-A1 | POLYMER | WARWICK EFFECT POLYMERS LTD (US) | 2013-11-07 | — | — | US | disclosed |
| US-20130295040-A1 | POLYMER | WARWICK EFFECT POLYMERS LTD (US) | 2013-11-07 | — | — | US | disclosed |
| US-8436104-B2 | Polymer | WARWICK EFFECT POLYMERS LIMITED (GB) | 2013-05-07 | — | — | US | disclosed |
| US-7811551-B2 | Imaging agents | GE HEALTHCARE AS (NO) | 2010-10-12 | — | — | US | disclosed |
| EP-1648925-A1 | BICYCLIC PEPTIDE IMAGING AGENTS | Amersham Health AS (NO) | 2006-04-26 | — | — | EP | disclosed |
| EP-1549317-A1 | IMPROVED IMAGING AGENTS COMPRISING BARBITURIC ACID DERIVATIVES | GE Healthcare Limited (GB) | 2005-07-06 | — | — | EP | disclosed |
| US-20050142061-A1 | Radiofluorination methods | GE HEALTHCARE LIMITED (GB) | 2005-06-30 | — | — | US | disclosed |
| WO-2005049005-A1 | INHIBITOR IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005012335-A1 | IMAGING AGENTS | AMERSHAM HEALTH AS (NO) | 2005-02-10 | — | — | WO | disclosed |
| WO-2005012335-A1 | IMAGING AGENTS | AMERSHAM HEALTH AS (NO) | 2005-02-10 | — | — | WO | disclosed |
| EP-1487762-A1 | RADIOFLUORINATION METHODS | Amersham plc (GB) | 2004-12-22 | — | — | EP | disclosed |
| WO-2004032936-A1 | IMPROVED IMAGING AGENTS COMPRISING BARBITURIC ACID DERIVATIVES | AMERSHAM PLC (GB) | 2004-04-22 | — | — | WO | disclosed |
| WO-2003080544-A1 | RADIOFLUORINATION METHODS | AMERSHAM PLC (GB) | 2003-10-02 | — | — | WO | disclosed |
| WO-1987007611-A1 | PROCESS FOR DNA LABELLING | EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (E (DE) | 1987-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312538-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (1S, 4S, 7Z, 10S, 16E, 21R)-7-ETHYLDENE-4,21-BIS(1-METHYL-ETHYL)-2-OXA-12,13-DITHIA-5,8,20,23-TETRAAZABICYCLO [8.7.6]TRICOS-16-ENE-3, 6, 9, 19, 22-PENTONE | IL17A, HSD17B7, SULT1E1 | KIF11 1550/4885 |
| US-20050142061-A1 | Radiofluorination methods | SSTR4, VIP, SSTR5 | KIF11 1686/4885 |
| US-20130295040-A1 | POLYMER | PCNA, PARG, COASY | KIF11 3375/4885 |
| US-10562931-B2 | Process for the preparation of (1S, 4S, 7Z, 10S, 16E, 21R)-7-ethyldene-4,21-bis(1-methyl-ethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3, 6, 9, 19, 22-pentone | SULT1E1, IL17A, TET1 | KIF11 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.