Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 12/20 | 0.57 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.57 |
| ▸ | INPP5B | P32019 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573126 | 0.84 | INPPL1 (0.70) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL9645945 | 0.77 | INPPL1 (0.61) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL1903626 | 0.76 | INPPL1 (0.34) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL522291 | 0.76 | INPPL1 (0.59) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL29655758 | 0.76 | INPPL1 (0.59) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL5667875 | 0.74 | INPPL1 (0.63) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL4430897 | 0.74 | INPPL1 (0.57) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL31095030 | 0.74 | INPPL1 (0.57) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL19808 | 0.74 | INPPL1 (0.57) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL2472745 | 0.74 | INPPL1 (0.57) | INPPL1INPP5AINPP5BSRCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126953-A1 | CORTICOSTEROID LINKED BETA-AGONIST COMPOUNDS FOR USE IN THERAPY | GILEAD SCIENCES, INC. (US) | 2010-11-04 | — | — | WO | disclosed |