SCHEMBL3727899

SCHEMBL3727899

CC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)[C](C(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 4/20 0.39
▸ NMT2 O60551 1/20 0.38
▸ NMT1 P30419 1/20 0.38
▸ CTSL P07711 3/20 0.38
▸ CTSS P25774 3/20 0.38
▸ CTSK P43235 3/20 0.38
▸ APLNR P35414 2/20 0.38
▸ CTSH P09668 1/20 0.38
▸ TFPI P10646 1/20 0.37
▸ IL23R Q5VWK5 1/20 0.37
▸ C5AR1 P21730 1/20 0.37
▸ SLC15A2 Q16348 1/20 0.36
▸ OPRL1 P41146 1/20 0.36
▸ QRFPR Q96P65 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3725918 0.88 SLC15A2 (0.35) NMT2NMT1APLNRC5AR1SLC15A2
SCHEMBL3731630 0.86 NMT1 (0.48) NMT2NMT1TFPIOPRL1QRFPR
SCHEMBL3731142 0.86 NMT1 (0.42) NMT2NMT1APLNRC5AR1
SCHEMBL29614488 0.84 CTSL (0.46) CTSLCTSSCTSKAPLNRCTSH
SCHEMBL29614491 0.84 CTSL (0.46) CTSLCTSSCTSKAPLNRCTSH
SCHEMBL14479383 0.81 TFPI (0.46) CTSLCTSSCTSKAPLNRCTSH
SCHEMBL29614462 0.79 TFPI (0.46) CTSLCTSSCTSKAPLNRCTSH
SCHEMBL31437155 0.79 SLC15A2 (0.44) CTSLCTSSCTSKAPLNRCTSH
SCHEMBL30595069 0.79 SIRT6 (0.41) IL23RSLC15A2
SCHEMBL26446682 0.79 SLC15A2 (0.48) F2C5AR1SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100173835-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R F2 3508/4885NMT2 755/4885NMT1 1060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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