Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 3/20 | 0.44 |
| ▸ | JAK1 | P23458 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22872893 | 0.74 | MAP4K4 (0.49) | PKMHPGDSCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5452621 | 0.71 | LMNA (0.60) | LMNAHTTPAK1PKMHSD17B10 | |
| SCHEMBL13057427 | 0.71 | ADORA1 (0.50) | LMNAHTTPAK1PKMHSD17B10 | |
| SCHEMBL5458071 | 0.70 | LMNA (0.61) | LMNAHTTPAK1PKMHSD17B10 | |
| SCHEMBL797230 | 0.70 | LMNA (0.61) | LMNAHTTPAK1PKMHSD17B10 | |
| SCHEMBL9202451 | 0.70 | HTT (1.00) | LMNAHTTPAK1PKMHSD17B10 | |
| SCHEMBL797231 | 0.69 | LMNA (1.00) | LMNAHTTPAK1PKMHSD17B10 | |
| SCHEMBL1322040 | 0.68 | ADORA1 (1.00) | PKMCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL11832616 | 0.68 | YTHDC1 (0.59) | LMNAHTTPAK1PKMHSD17B10 | |
| SCHEMBL9205078 | 0.68 | LMNA (0.56) | LMNAHTTPAK1PKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9063122-B2 | Biomodulators for treatment or prevention of disease | GALLEGOS ALFREDO (MX) | 2015-06-23 | — | — | US | disclosed |
| US-20100130421-A1 | BIOMODULATORS FOR TREATMENT OR PREVENTION OF DISEASE | GALLEGOS ALFREDO | 2010-05-27 | — | — | US | disclosed |