SCHEMBL372836

SCHEMBL372836

O=C(O)CCCC(CC1CO1)(CC1CO1)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.34
SLC22A6 Q4U2R8 1/20 0.34
TSHR P16473 2/20 0.33
NFKB1 P19838 1/20 0.33
PMP22 Q01453 1/20 0.33
CAMK2A Q9UQM7 1/20 0.31
GABRR3 A8MPY1 1/20 0.30
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
HDAC3 O15379 1/20 0.30
GABBR2 O75899 1/20 0.30
CYP1A2 P05177 1/20 0.30
THRB P10828 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRR1 P24046 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRR2 P28476 1/20 0.30
SLC6A1 P30531 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370245 0.93 TSHR (0.40) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL11368819 0.93 TSHR (0.40) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL9549612 0.89 ALDH1A1 (0.33) CYP1A2THRBKMT2A
SCHEMBL30915481 0.86 MGLL (0.45) LMNA
SCHEMBL15282099 0.82 ALDH1A1 (0.47) LMNAKMT2A
SCHEMBL16322504 0.80 HTT (0.35)
SCHEMBL3648152 0.79 ALDH1A1 (0.44) SLC22A6TSHRKMT2AHDAC11
SCHEMBL11779500 0.78 ALDH1A1 (0.39) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL23236463 0.78 TP53 (0.30)
SCHEMBL3340672 0.77 ALDH1A1 (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013143881-A1 CARBOXYLIC ESTER OR POLYETHER ESTER AS PROCESSING AID FOR FLUORO RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2013-10-03 WO claimed
EP-2644648-A1 Carboxylic acid esters or polyetheresters as a processing aid for fluoro-rubbers LANXESS Deutschland GmbH (DE) 2013-10-02 EP claimed
EP-1082366-B1 AQUEOUS POLYMER DISPERSIONS BASED ON UNSATURATED HETEROCYCLIC MONOMERS AND USE IN CROSSLINKING PROCESSES RHODIA CHIMIE SA (FR) 2003-06-18 EP claimed
EP-0690063-B1 Purification method of phosphoric esters DAIHACHI CHEM IND (JP) 2001-08-29 EP claimed
EP-0545227-B1 Metallized polyester film capacitor MITSUBISHI POLYESTER FILM CORP (JP) 1999-01-27 EP claimed
EP-0608273-B1 UV-CURABLE SILICONE RELEASE COMPOSITIONS MINNESOTA MINING & MFG (US) 1997-05-28 EP claimed
EP-0495269-B1 Thermosetting reactive resin mixture, moulded article and coating made therefrom DAINIPPON INK & CHEMICALS (JP) 1997-03-05 EP claimed
EP-0608273-A1 UV-CURABLE SILICONE RELEASE COMPOSITIONS. MINNESOTA MINING & MFG (US) 1994-08-03 EP claimed
WO-1993008238-A1 UV-CURABLE SILICONE RELEASE COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-04-29 WO claimed
EP-0239804-B1 EPOXY RESINS BASED ON TETRAGLYCIDYL DIAMINES AND THE USE THEREOF FOR EPOXY SYSTEMS AND PREPREGS AMOCO CORPORATION (US) 1989-08-09 EP claimed
WO-2025068609-A1 PROCESS FOR PREPARING THERMOSETTING EPOXY RESINS KARL-FRANZENS-UNIVERSITÄT-GRAZ (AT) 2025-04-03 WO disclosed
EP-2725627-B1 SOLAR CELL SEALING FILM AND SOLAR CELL USING THE SEALING FILM BRIDGESTONE CORP (JP) 2016-08-10 EP disclosed
US-9206275-B2 Ketal ester derivatives SEGETIS, INC. (US) 2015-12-08 US disclosed
US-20140163127-A1 KETAL ESTER DERIVATIVES SEGETIS, INC. (US) 2014-06-12 US disclosed
US-20140142008-A1 Lubricant Compositions Comprising Epoxide Compounds BASF SE 2014-05-22 US disclosed
EP-0000971-A1 Poudery coating composition CHEMISCHE WERKE HÜLS AG (DE) 1979-03-07 EP disclosed
EP-0000722-A1 Process for the preparation of polyurethanes containing arylsulfonic acid alkyl ester groups BAYER AG (DE) 1979-02-21 EP disclosed
EP-0000723-A1 Polyhydroxy compounds containing urethane-aryl-sulfonic acid-hydroxyalkyl ester groups, process for their preparation and their use as reaction components for the preparation of polyurethane resins BAYER AG (DE) 1979-02-21 EP disclosed
US-4044189-A TEXTILES, RUBBER REINFORCED WITH POLYESTER FIBER INDUSTRIES, INC. (US) 1977-08-23 US disclosed
US-3960813-A ADNC BLENDSADIPODI(NITRILE CARBONATE) ATLANTIC RICHFIELD COMPANY (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140163127-A1 KETAL ESTER DERIVATIVES KAT6A, ALKBH3, PBK LMNA 1559/4885SLC22A6 2523/4885TSHR 4723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.