Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132540 | 0.92 | GBA1 (0.39) | GBA1SPHK1ALDH1A1TSHREPHX1 | |
| SCHEMBL11922826 | 0.90 | MME (0.36) | GBA1SPHK1TSHR | |
| SCHEMBL21237051 | 0.83 | GBA1 (0.42) | GBA1SPHK1EPHX1NAAAGNAI3 | |
| SCHEMBL10289167 | 0.81 | MME (0.37) | — | |
| SCHEMBL9214532 | 0.80 | EPHX1 (0.38) | GBA1SPHK1ALDH1A1TSHREPHX1 | |
| SCHEMBL9843071 | 0.80 | EPHX1 (0.38) | GBA1SPHK1ALDH1A1TSHREPHX1 | |
| SCHEMBL9210570 | 0.78 | TSHR (0.32) | ALDH1A1TSHREPHX1 | |
| SCHEMBL8950833 | 0.76 | — | — | |
| SCHEMBL11256415 | 0.74 | EPHX1 (0.37) | GBA1ALDH1A1TSHREPHX1NAAA | |
| SCHEMBL9208824 | 0.74 | EPHX1 (0.37) | GBA1ALDH1A1TSHREPHX1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825155-B2 | Oxindole derivative as feeding control agent | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090131398-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1935883-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131398-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | GPR119, OXTR, CCKAR | GBA1 3523/4885SPHK1 3388/4885ALDH1A1 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.