Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PARG | Q86W56 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722827 | 0.87 | NPC1 (0.40) | ALDH1A1PARGTLR4TLR2PARP1 | |
| SCHEMBL3720208 | 0.84 | FFAR1 (0.39) | PARGFFAR1PARP1PPARG | |
| SCHEMBL3726994 | 0.82 | ACACB (0.42) | ALDH1A1KDM4ESMN1; SMN2HPGDPARG | |
| SCHEMBL3721320 | 0.82 | TDP1 (0.43) | ALDH1A1LMNASMN1; SMN2PARGHTT | |
| SCHEMBL3719332 | 0.80 | STK39 (0.44) | RAB9ASMN1; SMN2PARGMEN1KMT2A | |
| SCHEMBL3727617 | 0.80 | PPARA (0.44) | ALDH1A1LMNAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3719886 | 0.78 | TTR (0.42) | RAB9AALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL3720624 | 0.78 | ALDH1A1 (0.49) | RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3718523 | 0.77 | PARG (0.34) | KDM4EPARGMEN1KMT2AFFAR1 | |
| SCHEMBL3719235 | 0.76 | MEN1 (0.58) | RAB9AALDH1A1LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |