Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 4/20 | 0.68 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536948 | 0.89 | GABBR2 (0.66) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL503819 | 0.89 | GABBR2 (0.76) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL6734410 | 0.86 | GABBR2 (0.73) | GABBR2GABBR1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7092228 | 0.86 | GABBR2 (0.73) | GABBR2GABBR1MAPTMEN1KMT2A | |
| Alcohol SCHEMBL28575312 | 0.85 | GABBR2 (0.66) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL8192677 | 0.83 | CYP2D6 (0.56) | GABBR2GABBR1MAPTLMNACYP2C19 | |
| SCHEMBL1059563 | 0.83 | CYP2D6 (0.56) | GABBR2GABBR1MAPTLMNACYP2C19 | |
| SCHEMBL4445085 | 0.83 | GABBR2 (0.48) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL8187229 | 0.83 | CYP2D6 (0.56) | GABBR2GABBR1MAPTLMNACYP2C19 | |
| SCHEMBL1923826 | 0.83 | GABBR2 (0.63) | GABBR2GABBR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238107-A1 | PROCESS FOR THE MANUFACTURE OF A 6-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE DERIVATIVE | Boehringer Ingelheim International GmbH (DE) | 2010-10-13 | — | — | EP | claimed |
| WO-2009092580-A1 | PROCESS FOR THE MANUFACTURE OF A 6-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE DERIVATIVE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-30 | — | — | WO | claimed |
| JP-11315064-A | — | — | None | — | — | JP | disclosed |
| CN-111083927-A | Lipophilic macrocyclic ligands, complexes thereof and medical uses thereof | 法国加柏公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-100546969-C | Split the method for 2-methylol-3-phenylpropionic acid optical isomer | SHANGHAI INST OF MEDICINE INDU (CN) | 2009-10-07 | — | — | CN | disclosed |
| CN-100546969-C | Split the method for 2-methylol-3-phenylpropionic acid optical isomer | SHANGHAI INST OF MEDICINE INDU (CN) | 2009-10-07 | — | — | CN | disclosed |
| EP-0906900-B1 | A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid | AJINOMOTO KK (JP) | 2002-01-23 | — | — | EP | disclosed |
| JP-H11315064-A | PRODUCTION OF OPTICALLY ACTIVE PHENYLPROPIONIC ACID DERIVATIVE | AJINOMOTO CO INC | 1999-11-16 | — | — | JP | disclosed |
| EP-0906900-A1 | A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid | Ajinomoto Co., Inc. (JP) | 1999-04-07 | — | — | EP | disclosed |