Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 4/20 | 0.63 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 5/20 | 0.44 |
| ▸ | FNTB | P49356 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861865 | 0.89 | GABBR2 (0.59) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL14359785 | 0.86 | GABBR2 (0.66) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL503819 | 0.85 | GABBR2 (0.76) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL3681104 | 0.85 | CYP1A2 (0.53) | GABBR2GABBR1LMNACYP2C19ADORA3 | |
| SCHEMBL2878463 | 0.84 | GABBR2 (0.63) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL3728800 | 0.83 | GABBR2 (0.68) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL28529442 | 0.83 | ATM (0.59) | GABBR2GABBR1MAPTMEN1KMT2A | |
| SCHEMBL6780687 | 0.83 | FNTA (0.48) | GABBR2GABBR1MEN1KMT2AFNTA | |
| SCHEMBL6734410 | 0.83 | GABBR2 (0.73) | GABBR2GABBR1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7092228 | 0.83 | GABBR2 (0.73) | GABBR2GABBR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632903-B1 | COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF | WIGEN BIOMEDICINE TECH SHANGHAI CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |
| WO-2020002136-A1 | CATALYST BASED ON A BETA-SUBSTITUTED ESTER AND USE THEREOF IN A HYDROTREATMENT AND/OR HYDROCRACKING PROCESS | IFP Energies Nouvelles (FR) | 2020-01-02 | — | — | WO | disclosed |
| EP-1817312-B1 | MACROCYCLIC AMINOPYRIDYL BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK SHARP & DOHME (US) | 2011-06-08 | — | — | EP | disclosed |
| US-5830936-A | THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |