Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL8000989 | 0.93 | TP53 (0.50) | GABRR1RNPEPALDH1A1TSHRACE | |
| Ethylene Glycol SCHEMBL29686923 | 0.86 | RNPEP (0.48) | GABRR1RNPEPALDH1A1ACETDP1 | |
| Ethylene Glycol SCHEMBL1171441 | 0.86 | RNPEP (0.48) | GABRR1RNPEPALDH1A1ACETDP1 | |
| Ethylene Glycol SCHEMBL28854573 | 0.86 | RNPEP (0.48) | GABRR1RNPEPALDH1A1ACETDP1 | |
| Alanine SCHEMBL28071528 | 0.83 | GABRR1 (0.52) | GABRR1ALDH1A1TSHRSLC7A5ENPEP | |
| Monoethanolamine SCHEMBL28219640 | 0.83 | GABRR1 (0.52) | GABRR1RNPEPALDH1A1TSHRSLC7A5 | |
| Alanine SCHEMBL28071526 | 0.83 | GABRR1 (0.52) | GABRR1ALDH1A1TSHRSLC7A5ENPEP | |
| 1,4-Butanediol SCHEMBL4449579 | 0.81 | RNPEP (0.44) | RNPEPALDH1A1ACETDP1LMNA | |
| Lactic Acid SCHEMBL1831319 | 0.81 | TP53 (0.61) | GABRR1ALDH1A1TSHRLMNASLC7A5 | |
| Lactic Acid SCHEMBL22346344 | 0.81 | TP53 (0.61) | GABRR1ALDH1A1TSHRLMNASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985057-B | Improvements in or relating to depilatory compositions | RECKITT & COLMAN (OVERSEAS) LTD. (GB) | 2016-02-03 | — | — | CN | claimed |
| CN-103998014-A | Compositions | RECKITT & COLMAN OVERSEAS | 2014-08-20 | — | — | CN | claimed |
| CN-101312767-B | Improvements in or relating to cosmetic compositions | RECKITT BENCKISER UK LTD | 2013-06-12 | — | — | CN | claimed |
| CN-102985057-A | Improvements in or relating to depilatory compositions | RECKITT & COLMAN OVERSEAS | 2013-03-20 | — | — | CN | claimed |
| CN-1968676-A | Improvements in or relating to depilatory compositions | RECKITT BENCKISER UK LTD (GB) | 2007-05-23 | — | — | CN | claimed |
| CN-102985057-B | Improvements in or relating to depilatory compositions | RECKITT & COLMAN (OVERSEAS) LTD. (GB) | 2016-02-03 | — | — | CN | disclosed |
| CN-102762184-B | Flexible moisture depilatory article | THE PROCTER & GAMBLE CO. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-104994915-A | Stable personal care article | PROCTER & GAMBLE | 2015-10-21 | — | — | CN | disclosed |
| CN-104321112-A | Novel depilatory compositions | RECKITT & COLMAN OVERSEAS | 2015-01-28 | — | — | CN | disclosed |
| CN-104287986-A | Adherent depilatory article | PROCTER & GAMBLE | 2015-01-21 | — | — | CN | disclosed |
| CN-103841952-A | Depilatory method and kit | PROCTER & GAMBLE | 2014-06-04 | — | — | CN | disclosed |
| CN-103826603-A | Method and kit for hair removal | PROCTER & GAMBLE | 2014-05-28 | — | — | CN | disclosed |
| CN-101616655-A | Hair styling composition | SHISEIDO CO LTD | 2009-12-30 | — | — | CN | disclosed |
| CN-101342116-A | Structured depilatory compositions | MCNEIL PPC INC (US) | 2009-01-14 | — | — | CN | disclosed |
| CN-101312767-A | Improvements in or relating to cosmetic compositions | RECKITT BENCKISER UK LTD (GB) | 2008-11-26 | — | — | CN | disclosed |
| US-20080241854-A1 | KITS AND METHODS FOR EVALUATING HAIR | L'OREAL S.A. (FR) | 2008-10-02 | — | — | US | disclosed |
| EP-1975613-A1 | Kits and methods for evaluating hair | L'OREAL (FR) | 2008-10-01 | — | — | EP | disclosed |
| US-20080085249-A1 | Artificial hair color removal compositions and methods | L'OREAL (FR) | 2008-04-10 | — | — | US | disclosed |
| CN-1968676-A | Improvements in or relating to depilatory compositions | RECKITT BENCKISER UK LTD (GB) | 2007-05-23 | — | — | CN | disclosed |
| CN-1337873-A | External composition | SHISEIDO CO LTD (JP) | 2002-02-27 | — | — | CN | disclosed |