SCHEMBL3729436

SCHEMBL3729436

O=C(O)COc1c(Cl)cccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 1.00
CD69 Q07108 4/20 0.58
ALOX15 P16050 1/20 0.52
PTGDR2 Q9Y5Y4 2/20 0.51
HIF1A Q16665 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
AKR1B1 P15121 1/20 0.50
PTPN7 P35236 1/20 0.49
PTPN12 Q05209 1/20 0.49
PTPN22 Q9Y2R2 1/20 0.49
MCL1 Q07820 1/20 0.47
KDM4E B2RXH2 2/20 0.46
LMNA P02545 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
PKM P14618 1/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28731750 0.87 KMT2A (0.77) KMT2ACD69ALOX15PTGDR2HIF1A
SCHEMBL1887188 0.87 KMT2A (0.77) KMT2ACD69ALOX15PTGDR2HIF1A
SCHEMBL7172967 0.85 KMT2A (0.74) KMT2ACD69AKR1B1PTPN7PTPN12
SCHEMBL18095828 0.84 KMT2A (0.72) KMT2ACD69ALOX15PTGDR2HIF1A
SCHEMBL9505425 0.83 KMT2A (0.71) KMT2ACD69AKR1B1PTPN7PTPN12
SCHEMBL22307856 0.82 KMT2A (0.69) KMT2ACD69AKR1B1PTPN7PTPN12
SCHEMBL30435946 0.82 KMT2A (0.69) KMT2ACD69ALOX15PTGDR2HIF1A
SCHEMBL11514166 0.81 KMT2A (0.68) KMT2AALOX15HIF1ATDP1PTPN7
SCHEMBL9780958 0.80 KMT2A (0.67) KMT2ACD69AKR1B1MCL1LMNA
SCHEMBL9646424 0.79 KMT2A (0.66) KMT2ACD69ALOX15HIF1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119125340-A Method for measuring phenol-containing substance in 2, 4-drop recovery liquid 湖北兴晨科技有限公司 2024-12-13 CN claimed
CN-101230007-B Novel technique for producing 2,6-dichloro diphenylamine JINGQUAN ZHAO 2010-08-04 CN claimed
CN-101230007-A Novel technique for producing 2,6-dichloro diphenylamine JINGQUAN ZHAO (CN) 2008-07-30 CN claimed
EP-1217884-B1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2007-02-21 EP claimed
US-6897065-B1 Method for maturation of conifer somatic embryos WOODY PLANT BIOTECH APS (DK) 2005-05-24 US claimed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP claimed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO claimed
EP-0380712-B1 Process for the preparation of 2,6-dichlorodiphenylaminoacetic-acid derivatives HEUMANN PHARMA GMBH & CO (DE) 1995-01-04 EP claimed
US-4978773-A Process for the preparation of 2,6-dichlorodiphenylaminoacetic acid derivatives HEUMANN PHARMA GMBH & CO. (DE) 1990-12-18 US claimed
JP-2215750-A None JP disclosed
CN-118271158-B Method for synthesizing deuterium-labeled substance containing deuterium atom structural unit 山东大学 2026-05-12 CN disclosed
US-12534649-B2 Radiation-curable organopolysiloxane composition and a release sheet SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-01-27 US disclosed
EP-4673137-A1 NBD1 MODULATORS AND METHODS OF USING THE SAME Sionna Therapeutics Inc. (US) 2026-01-07 EP disclosed
WO-2025073702-A1 PROCESS FOR PREPARING AROMATIC AMINES FROM ARYL CHLORIDES BASF SE (DE) 2025-04-10 WO disclosed
EP-0257378-A1 Pyrimidine derivatives, their preparation and medicaments containing these derivatives F. HOFFMANN-LA ROCHE AG (CH) 1988-03-02 EP disclosed
EP-0146297-B1 SUBSTITUTED TRANS-1,2-DIAMINOCYCLOHEXYL AMIDE COMPOUNDS WARNER-LAMBERT COMPANY (US) 1988-02-03 EP disclosed
US-4677122-A ANALGESICS, DIURETICS WARNER-LAMBERT COMPANY (US) 1987-06-30 US disclosed
US-4598087-A DIURETICS; ANALGESICS, PSYCHOTHERAPEUTICS WARNER-LAMBERT COMPANY (US) 1986-07-01 US disclosed
EP-0146297-A1 Substituted trans-1,2-diaminocyclohexyl amide compounds WARNER-LAMBERT COMPANY (US) 1985-06-26 EP disclosed
US-4245005-A CHROMATOGRAPHY, CROSSLINKED COATING PURDUE RESEARCH FOUNDATION (US) 1981-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534649-B2 Radiation-curable organopolysiloxane composition and a release sheet RAD51, MSR1, RAD1 KMT2A 2604/4885CD69 4732/4885ALOX15 2780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.