Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | CD69 | Q07108 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561402 | 0.84 | PTGDR2 (0.57) | KMT2ACD69ALOX15TSHRHSD17B10 | |
| SCHEMBL4483469 | 0.82 | ALDH1A1 (0.49) | KMT2ACD69HSD17B10PKMKDM4E | |
| SCHEMBL23980841 | 0.81 | NPC1 (0.50) | KMT2AALOX15PTPN1KDM4EALDH1A1 | |
| SCHEMBL3729436 | 0.79 | KMT2A (1.00) | KMT2ACD69ALOX15PKMLMNA | |
| SCHEMBL8954486 | 0.79 | AKR1B1 (0.57) | KMT2AALOX15TSHRHSD17B10PTPN1 | |
| SCHEMBL23273092 | 0.79 | KMT2A (0.42) | KMT2ACD69ALOX15TSHRHSD17B10 | |
| SCHEMBL3241147 | 0.78 | PKM (0.64) | KMT2AALOX15PKMLMNAKDM4E | |
| SCHEMBL1145948 | 0.77 | KMT2A (0.62) | KMT2ACD69ALOX15HSD17B10PKM | |
| SCHEMBL6746937 | 0.76 | THRB (0.54) | KMT2AALOX15TSHRHSD17B10PKM | |
| SCHEMBL2014943 | 0.76 | KMT2A (0.61) | KMT2ACD69ALOX15LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257011-B1 | PERMEATION MODIFIED ASYMMETRIC GAS SEPARATION MEMBRANES HAVING GRADED DENSITY SKINS | PERMEA, Inc. (US) | 1992-10-07 | — | — | EP | disclosed |
| US-4728346-A | PERMSELECTIVITY | PERMEA INC. (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0257011-A2 | Permeation modified asymmetric gas separation membranes having graded density skins | PERMEA, Inc. (US) | 1988-02-24 | — | — | EP | disclosed |
| US-4575385-A | POLYSULFONES CONTACTED WITH BENZENE COMPOUND | MONSANTO COMPANY (US) | 1986-03-11 | — | — | US | disclosed |