SCHEMBL3729490

SCHEMBL3729490

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nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP9 P14780 1/20 0.32
MMP13 P45452 1/20 0.32
KDM4E B2RXH2 2/20 0.32
PRKCA P17252 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5456012 0.95 MMP1 (0.33) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7551872 0.90 MMP1 (0.42) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL5668111 0.86 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL16914934 0.86 PDE4A (0.40) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL10360445 0.84 LMNA (0.33) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7096392 0.83 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL4603930 0.83 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL491478 0.81 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL4603634 0.81 MAPT (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL15145984 0.80 USP2 (0.45) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120142618-A1 KETOGENIC SACCHARIDES BTG INTERNATIONAL LIMITED (GB) 2012-06-07 US disclosed
US-7758744-B2 Dual glucose-turbidimetric analytical sensors ZWEIG STEPHEN ELIOT 2010-07-20 US disclosed
US-20070225252-A1 Ketogenic Saccharides BTG INTERNATIONAL LIMITED (GB) 2007-09-27 US disclosed
EP-1778212-A2 KETOGENIC SACCHARIDES KETOCYTONYX INC. (US) 2007-05-02 EP disclosed
US-20060051738-A1 Dual glucose-turbidimetric analytical sensors ZWEIG STEPHEN E 2006-03-09 US disclosed
WO-2006012490-A2 KETOGENIC SACCHARIDES KETOCYTONYX INC. (US) 2006-02-02 WO disclosed
US-6984307-B2 Dual glucose-hydroxybutyrate analytical sensors ZWEIG STEPHEN ELIOT 2006-01-10 US disclosed
US-20030068666-A1 Dual glucose-hydroxybutyrate analytical sensors ZWEIG STEPHEN ELIOT (US) 2003-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070225252-A1 Ketogenic Saccharides MGAM, KHK, GCKR LMNA 1866/4885L3MBTL1 1721/4885PDE4A 3784/4885
US-20120142618-A1 KETOGENIC SACCHARIDES MGAM, GCKR, KHK LMNA 1722/4885L3MBTL1 1776/4885PDE4A 3970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.