Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.54 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302000 | 0.82 | OGG1 (1.00) | OGG1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL3727333 | 0.81 | GAA (0.73) | GAAATMKMT2AALDH1A1KDM4E | |
| SCHEMBL10727418 | 0.80 | OGG1 (0.74) | OGG1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1614613 | 0.80 | KDM4E (0.72) | OGG1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL3733772 | 0.79 | GAA (0.71) | GAAATMMEN1KMT2AALDH1A1 | |
| SCHEMBL3738177 | 0.79 | GAA (0.71) | GAAATMMEN1KMT2AALDH1A1 | |
| SCHEMBL6846901 | 0.79 | OGG1 (0.72) | OGG1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4908724 | 0.78 | KDM4E (0.74) | OGG1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL3725265 | 0.77 | ATM (0.68) | GAAATMMEN1KMT2AALDH1A1 | |
| SCHEMBL28325522 | 0.77 | OGG1 (0.89) | OGG1GAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | OGG1 4123/4885GAA 735/4885ATM 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.