Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 12/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813981 | 0.84 | GHSR (0.41) | GHSRMC4RTACR1MET | |
| SCHEMBL3804821 | 0.82 | GHSR (0.39) | GHSRMC4RTACR1LMNASMN1; SMN2 | |
| SCHEMBL3731664 | 0.82 | GHSR (0.63) | GHSRMC4RTACR1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL3728776 | 0.81 | GHSR (0.62) | GHSRMC4RTACR1KDM4ELMNA | |
| SCHEMBL3750634 | 0.78 | GHSR (0.69) | GHSRTACR1HRH4KDM4EMEN1 | |
| SCHEMBL3806409 | 0.78 | GHSR (0.41) | GHSRMC4RTACR1HIF1A | |
| SCHEMBL3725764 | 0.78 | GHSR (0.40) | GHSRTACR1 | |
| SCHEMBL3727091 | 0.78 | GHSR (0.39) | GHSRMC4RTACR1METHIF1A | |
| SCHEMBL3809201 | 0.77 | GHSR (0.43) | GHSRMC4RTACR1KDM4ELMNA | |
| SCHEMBL3733869 | 0.77 | GHSR (0.48) | GHSRTACR1METKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | claimed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | claimed |
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |