Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725764 | 0.90 | GHSR (0.40) | GHSRGPBAR1TRPV1TACR1 | |
| SCHEMBL3731664 | 0.84 | GHSR (0.63) | GHSRLMNASMN1; SMN2TACR1CCR3 | |
| Hydrochloric Acid SCHEMBL3728776 | 0.83 | GHSR (0.62) | GHSRLMNASMN1; SMN2TACR1CCR3 | |
| SCHEMBL3809201 | 0.83 | GHSR (0.43) | GHSRLMNASMN1; SMN2TACR1HSP90AA1 | |
| SCHEMBL3633463 | 0.79 | GHSR (0.73) | GHSRLMNASMN1; SMN2UGCGCYP3A4 | |
| SCHEMBL3806409 | 0.79 | GHSR (0.41) | GHSRTACR1CCR3 | |
| SCHEMBL3804821 | 0.79 | GHSR (0.39) | GHSRLMNASMN1; SMN2TACR1CCR3 | |
| SCHEMBL3730182 | 0.77 | GHSR (0.43) | GHSRLMNASMN1; SMN2TACR1MET | |
| SCHEMBL3813981 | 0.77 | GHSR (0.41) | GHSRTACR1MET | |
| SCHEMBL3727091 | 0.76 | GHSR (0.39) | GHSRCYP3A4TACR1CCR3MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |