Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.67 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.62 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838642 | 0.89 | ESR2 (0.69) | ESR2NR1H2ABHD6MAPK1HDAC1 | |
| SCHEMBL16775738 | 0.85 | NR1H2 (0.69) | ESR2NR1H2ABHD6MAPK1HDAC1 | |
| SCHEMBL25176924 | 0.84 | NR1H2 (0.67) | ESR2NR1H2ABHD6MAPK1HDAC1 | |
| SCHEMBL30097009 | 0.84 | NR1H2 (0.67) | ESR2NR1H2ABHD6MAPK1HDAC1 | |
| SCHEMBL3730293 | 0.84 | ESR2 (0.62) | ESR2NR1H2 | |
| SCHEMBL3730457 | 0.83 | ESR2 (0.61) | ESR2NR1H2ABHD6MAPK1HDAC1 | |
| SCHEMBL29377835 | 0.82 | NR1H2 (0.90) | ESR2NR1H2ABHD6MAPK1HDAC1 | |
| SCHEMBL61143 | 0.82 | NR1H2 (0.90) | ESR2NR1H2ABHD6MAPK1HDAC1 | |
| SCHEMBL31067462 | 0.82 | ESR2 (0.74) | ESR2NR1H2ABHD6MAPK1HDAC1 | |
| SCHEMBL19660818 | 0.82 | ESR2 (0.60) | ESR2NR1H2ABHD6MAPK1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829070-B2 | molar excess of anionic groups; acrylic acid or methacrylic acid; (meth)acrylates; free radically-polymerizable unsaturated amino monomer; water soluble; elastic and strong hairspray; coating material for a solid dosage form; adhesive | BASF SE (DE) | 2010-11-09 | — | — | US | claimed |
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | SARMA PAKALA KUMARA SAVITHRU | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | ACACA, ACACB, PC | ESR2 3134/4885NR1H2 575/4885ABHD6 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.