Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 11/20 | 0.43 |
| ▸ | KLRK1 | P26718 | 7/20 | 0.42 |
| ▸ | MICA | Q29983 | 7/20 | 0.42 |
| ▸ | RAET1L | Q5VY80 | 5/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722374 | 0.91 | MTTP (0.45) | MTTPKLRK1MICARAET1LSCN1A | |
| SCHEMBL3737476 | 0.87 | MTTP (0.48) | MTTPKLRK1MICARAET1LSCN1A | |
| SCHEMBL3727528 | 0.83 | MTTP (0.43) | MTTPKLRK1MICARAET1L | |
| SCHEMBL3729241 | 0.79 | MTTP (0.45) | MTTPKLRK1MICARAET1L | |
| SCHEMBL3730525 | 0.76 | RORC (0.36) | MTTPKLRK1MICARAET1LSCN1A | |
| SCHEMBL3727083 | 0.75 | MTTP (0.48) | MTTPKLRK1MICARAET1L | |
| SCHEMBL6715449 | 0.68 | MTTP (0.55) | MTTP | |
| SCHEMBL6718895 | 0.67 | MTTP (0.52) | MTTPKLRK1MICARAET1L | |
| SCHEMBL6719615 | 0.67 | MTTP (0.52) | MTTPKLRK1MICARAET1L | |
| SCHEMBL6719432 | 0.67 | MTTP (0.54) | MTTPKLRK1MICARAET1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. | 2010-06-24 | — | — | US | claimed |
| US-20050075367-A1 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | US | claimed |
| EP-1479666-A1 | ESTER COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-11-24 | — | — | EP | claimed |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. | 2010-06-24 | — | — | US | disclosed |
| US-7625948-B2 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20050075367-A1 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | US | disclosed |
| EP-1479666-A1 | ESTER COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075367-A1 | Ester compound and medicinal use thereof | LIPC, CES1, MTTP | MTTP 3/4885KLRK1 3360/4885MICA 3630/4885 |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | LIPC, CES1, MTTP | MTTP 3/4885KLRK1 3855/4885MICA 3640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.