Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839847 | 0.78 | ALDH1A1 (0.50) | ABL1ABCB1BCRMMP3BCL2L1 | |
| SCHEMBL344517 | 0.78 | ABL1 (0.50) | ABL1ABCB1BCRMMP3BCL2L1 | |
| SCHEMBL26136549 | 0.78 | ABL1 (0.50) | ABL1ABCB1BCRMMP3BCL2L1 | |
| SCHEMBL11841403 | 0.76 | SLC13A5 (0.52) | SLC13A5CYP2C9ALDH1A1PPARGPPARA | |
| SCHEMBL11430414 | 0.75 | ABL1 (0.41) | ABL1ABCB1BCRMMP3BCL2L1 | |
| SCHEMBL2392972 | 0.75 | AKR1C3 (0.43) | SLC13A5RAB9AALDH1A1HSD17B10CES2 | |
| SCHEMBL16815415 | 0.74 | ALDH1A1 (0.56) | CYP2C9LMNAMAPTRAB9AKMT2A | |
| SCHEMBL891405 | 0.74 | ALDH1A1 (0.56) | CYP2C9LMNAMAPTRAB9AKMT2A | |
| SCHEMBL28463446 | 0.73 | KMT2A (0.38) | SLC13A5BCL2L1CYP2C9MEN1KMT2A | |
| SCHEMBL27989193 | 0.72 | ABL1 (0.48) | ABL1ABCB1BCRMMP3BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278759-A1 | Topical Therapeutic Delivery System | MURAD HOWARD | 2010-11-04 | — | — | US | disclosed |
| WO-2007117352-A2 | TOPICAL THERAPEUTIC DELIVERY SYSTEM | MURAD HOWARD (US) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007092085-A2 | FRAGRANCED THERAPEUTIC DELIVERY SYSTEM | MURAD HOWARD (US) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278759-A1 | Topical Therapeutic Delivery System | LIPA, HCAR3, HTR2B | SLC13A5 4005/4885ABL1 2348/4885ABCB1 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.