SCHEMBL3731386

SCHEMBL3731386

COc1c2ccccc2c(OC)c2c(-c3ccc(C)cc3)c3ccccc3c(-c3ccc(C)cc3)c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.41
ACHE P22303 1/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40
TUBA1A Q71U36 1/20 0.40
TUBA1C Q9BQE3 1/20 0.40
TUBB6 Q9BUF5 1/20 0.40
TUBB2B Q9BVA1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3723473 0.86 KDM4E (0.56) ALDH1A1SMN1; SMN2MAPK1KDM4EPOLB
SCHEMBL3722164 0.82 ACHE (0.48) ALDH1A1SMN1; SMN2MAPK1KDM4EACHE
SCHEMBL3728190 0.81 KDM4E (0.45) ALDH1A1SMN1; SMN2MAPK1KDM4EPOLB
SCHEMBL3724955 0.78 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2MAPK1KDM4EPOLB
SCHEMBL3477351 0.77 ACHE (0.57) ALDH1A1SMN1; SMN2MAPK1KDM4EPOLB
SCHEMBL30742831 0.77 ACHE (0.57) ALDH1A1SMN1; SMN2MAPK1KDM4EPOLB
SCHEMBL13241188 0.77 ACHE (0.60) ALDH1A1SMN1; SMN2MAPK1KDM4EACHE
SCHEMBL24605249 0.76 KDM4E (0.48) ALDH1A1SMN1; SMN2MAPK1KDM4EPOLB
SCHEMBL3725219 0.76 DHODH (0.42) ALDH1A1SMN1; SMN2MAPK1KDM4ERAB9A
SCHEMBL5861425 0.75 GSK3B (0.40) ALDH1A1SMN1; SMN2MAPK1KDM4EACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070141747-A1 Electronic device fabrication process XEROX CORPORATION 2007-06-21 US claimed
US-7651885-B2 Electronic device fabrication process XEROX CORPORATION (US) 2010-01-26 US disclosed
US-20070141747-A1 Electronic device fabrication process XEROX CORPORATION 2007-06-21 US disclosed