SCHEMBL3731468

SCHEMBL3731468

C=CC(N)SOSC(N)C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7285763 0.69
SCHEMBL1814736 0.69
SCHEMBL530364 0.68 CA2 (0.30)
SCHEMBL1176679 0.65
SCHEMBL18396189 0.65
SCHEMBL1814739 0.65
SCHEMBL10815836 0.62
SCHEMBL10822015 0.62
SCHEMBL11322791 0.62
SCHEMBL899543 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5399552-A Antibiotic peptides bearing aminoalkylthioether moieties MERCK & CO, INC (US) 1995-03-21 US claimed
EP-0538002-A1 Aminoalkyl thioether compounds MERCK & CO. INC. (US) 1993-04-21 EP claimed
JP-5239096-A None JP disclosed
CN-113227092-A Compounds and methods of use thereof for treating cancer 亚瑞克西斯制药公司 2021-08-06 CN disclosed
CN-105764850-B Method and apparatus for preparing functionalized graphene and functionalized graphene 韩华化学株式会社 2018-01-12 CN disclosed
CN-105764850-A Method and apparatus for preparing functionalized graphene and functionalized graphene 韩化石油化学株式会社 2016-07-13 CN disclosed
EP-2140264-A1 METHODS OF USE OF SOLID SUPPORT MATERIAL FOR BINDING BIOMOLECULES 3M Innovative Properties Company (US) 2010-01-06 EP disclosed
WO-2008131063-A1 METHODS OF USE OF SOLID SUPPORT MATERIAL FOR BINDING BIOMOLECULES 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-30 WO disclosed
EP-1689709-A1 N-SULFONYLDICARBOXIMIDE CONTAINING TETHERING COMPOUNDS 3M Innovative Properties Company (US) 2006-08-16 EP disclosed
WO-2005049565-A1 N-SULFONYLDICARBOXIMIDE CONTAINING TETHERING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-06-02 WO disclosed
US-5516757-A ANTIFUNGAL MERCK & CO., INC. (US) 1996-05-14 US disclosed
WO-1996008267-A1 SEMI-SYNTHETIC LIPOPEPTIDES, COMPOSITIONS CONTAINING SAID LIPOPEPTIDES, AND METHODS OF USE MERCK & CO., INC. (US) 1996-03-21 WO disclosed
US-5399552-A Antibiotic peptides bearing aminoalkylthioether moieties MERCK & CO, INC (US) 1995-03-21 US disclosed
US-5399552-A Antibiotic peptides bearing aminoalkylthioether moieties MERCK & CO, INC (US) 1995-03-21 US disclosed
JP-H05239096-A AMINOALKYLTHIOETHER COMPOUND MERCK & CO INC 1993-09-17 JP disclosed
EP-0538002-A1 Aminoalkyl thioether compounds MERCK & CO. INC. (US) 1993-04-21 EP disclosed
EP-0538002-A1 Aminoalkyl thioether compounds MERCK & CO. INC. (US) 1993-04-21 EP disclosed