Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956103 | 1.00 | HDAC9 (0.43) | HDAC9AKR1C1KIF11EDNRBEDNRA | |
| SCHEMBL1404156 | 0.88 | HDAC9 (0.41) | HDAC9AKR1C1KIF11EDNRBEDNRA | |
| SCHEMBL30685517 | 0.88 | HDAC9 (0.41) | HDAC9AKR1C1KIF11EDNRBEDNRA | |
| SCHEMBL1404157 | 0.88 | HDAC9 (0.41) | HDAC9AKR1C1KIF11EDNRBEDNRA | |
| SCHEMBL1404158 | 0.88 | HDAC9 (0.41) | HDAC9AKR1C1KIF11EDNRBEDNRA | |
| SCHEMBL30685518 | 0.81 | HDAC9 (0.36) | HDAC9KIF11EDNRBEDNRAMEN1 | |
| SCHEMBL28389144 | 0.81 | OPRM1 (0.50) | EDNRBEDNRA | |
| SCHEMBL22159666 | 0.81 | HDAC9 (0.36) | HDAC9KIF11EDNRBEDNRAMEN1 | |
| SCHEMBL27956109 | 0.81 | OPRM1 (0.50) | EDNRBEDNRA | |
| SCHEMBL15568975 | 0.80 | HDAC9 (0.34) | HDAC9KIF11EDNRBEDNRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757604-B1 | PROCESS FOR PRODUCING SOLIFENACIN OR ITS SALT | ASTELLAS PHARMA INC (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-7829715-B2 | Method for producing solifenacin or salts thereof | ASTELLAS PHARMA INC. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20070185329-A1 | Method for producing solifenacin or salts thereof | ASTELLAS PHARMA INC. | 2007-08-09 | — | — | US | disclosed |
| EP-1757604-A1 | PROCESS FOR PRODUCING SOLIFENACIN OR ITS SALT | Astellas Pharma Inc. (JP) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005105795-A1 | PROCESS FOR PRODUCING SOLIFENACIN OR ITS SALT | ASTELLAS PHARMA INC. (JP) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185329-A1 | Method for producing solifenacin or salts thereof | SUCNR1, GLS, CACNA1S | HDAC9 1889/4885AKR1C1 929/4885KIF11 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.