Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.38 |
| ▸ | CDC25B | P30305 | 6/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.38 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732120 | 1.00 | ALDH1A1 (0.39) | ALDH1A1FOLH1PTPN1CDC25BPTPN2 | |
| SCHEMBL3738997 | 1.00 | ALDH1A1 (0.39) | ALDH1A1FOLH1PTPN1CDC25BPTPN2 | |
| SCHEMBL16387534 | 0.91 | ALDH1A1 (0.36) | ALDH1A1FOLH1PTPN1CDC25BPTPN2 | |
| SCHEMBL16387476 | 0.91 | ALDH1A1 (0.36) | ALDH1A1FOLH1PTPN1CDC25BPTPN2 | |
| SCHEMBL13734628 | 0.84 | FOLH1 (0.42) | ALDH1A1FOLH1PTPN1CDC25BPTPN2 | |
| SCHEMBL13734630 | 0.84 | FOLH1 (0.42) | ALDH1A1FOLH1PTPN1CDC25BPTPN2 | |
| SCHEMBL16387590 | 0.81 | ITGA4 (0.38) | ALDH1A1PTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL15589990 | 0.77 | FOLH1 (0.40) | FOLH1MMP2MMP9MMP8TACR1 | |
| SCHEMBL16387592 | 0.76 | CA12 (0.34) | ALDH1A1PTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL3784370 | 0.76 | PTPN1 (0.42) | PTPN1CDC25BPTPN2CDC25AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722014-B2 | 1 H-[1, 2, 3] triazole substituted amino acids and uses thereof | WASHINGTON UNIVERSITY (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722014-B2 | 1 H-[1, 2, 3] triazole substituted amino acids and uses thereof | WASHINGTON UNIVERSITY (US) | 2014-05-13 | — | — | US | disclosed |
| US-20100278732-A1 | 1H-[1, 2, 3] TRIAZOLE SUBSTITUTED AMINO ACIDS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278732-A1 | 1H-[1, 2, 3] TRIAZOLE SUBSTITUTED AMINO ACIDS AND USES THEREOF | SLC7A1, SLC1A5, SLC1A3 | ALDH1A1 2092/4885FOLH1 165/4885PTPN1 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.