Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382966 | 0.82 | DAO (0.50) | DAOALOX15F11LMNA | |
| SCHEMBL3735562 | 0.81 | KDR (0.55) | FLT3PDGFRBALOX15MAOBLMNA | |
| SCHEMBL3736490 | 0.81 | DAO (0.58) | DAOALOX15F11LMNA | |
| SCHEMBL11689245 | 0.78 | DAO (0.46) | DAOALOX15F11LMNA | |
| SCHEMBL3746420 | 0.78 | XDH (0.41) | FLT3PDGFRBDAOALOX15DRD2 | |
| SCHEMBL3745629 | 0.77 | MAOB (0.38) | DAOALOX15MAOBDRD2DRD3 | |
| SCHEMBL3735598 | 0.76 | DAO (0.35) | DAOALOX15MAOBDRD2DRD3 | |
| SCHEMBL3745791 | 0.75 | MOGAT2 (0.35) | DAOALOX15MAOBDRD2DRD3 | |
| SCHEMBL3738420 | 0.75 | MOGAT2 (0.35) | DAOALOX15MAOBDRD2DRD3 | |
| SCHEMBL3741631 | 0.75 | MOGAT2 (0.35) | DAOALOX15MAOBDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |