Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732166 | 0.81 | FLT3 (0.48) | LMNAPDGFRBFLT3MAOBALOX15 | |
| SCHEMBL3738061 | 0.80 | KDR (0.65) | KDRCHEK1KDM4EALDH1A1MAPT | |
| SCHEMBL11650959 | 0.76 | RAB9A (0.63) | KDRCHEK1KDM4EALDH1A1MAPT | |
| SCHEMBL11661055 | 0.74 | KDM4E (0.76) | KDRCHEK1KDM4EALDH1A1MAPT | |
| SCHEMBL3739265 | 0.74 | KDR (0.44) | KDRCHEK1KDM4EALDH1A1MAPT | |
| SCHEMBL19290 | 0.74 | KDR (0.61) | KDRCHEK1KDM4EALDH1A1MAPT | |
| SCHEMBL11053514 | 0.74 | CA12 (0.45) | KDRCHEK1KDM4EALDH1A1MAPT | |
| SCHEMBL6238750 | 0.74 | MAPT (0.60) | KDRCHEK1KDM4EALDH1A1MAPT | |
| SCHEMBL3742853 | 0.73 | KDR (0.43) | KDRCHEK1KDM4EALDH1A1MAPT | |
| SCHEMBL9384667 | 0.73 | KDM4E (0.63) | KDRCHEK1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |
| EP-1353908-B1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN INC (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1353908-A4 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN INC (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1353908-A1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN, INC. (US) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002059096-A1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| US-6410732-B2 | FORMATION OF BOND BETWEEN NITROGEN ATOM OF ACRIDAN RING AND CARBON ATOM OF ANOTHER AROMATIC OR HETEROAROMATIC RING COMPOUND; ASSAYS FOR PEROXIDASE ENZYMES AND ENZYME INHIBITORS AND IN ASSAYS EMPLOYING ENZYME-LABELED SPECIFIC BINDING PAIRS | LUMIGEN, INC. | 2002-06-25 | — | — | US | disclosed |
| US-20010031869-A1 | Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives | LUMIGEN, INC. | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031869-A1 | Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives | ALDH3A1, AADAC, SPR | KDR 4636/4885CHEK1 3164/4885KDM4E 2719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.