Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.62 |
| ▸ | DHODH | Q02127 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738947 | 0.92 | EPHX2 (0.69) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11747505 | 0.89 | HTT (0.81) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL3735037 | 0.87 | HTT (0.77) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL3730715 | 0.87 | HTT (0.77) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11745546 | 0.84 | HTT (0.72) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11748515 | 0.84 | HTT (0.81) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL26930816 | 0.84 | HTT (0.76) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4018109 | 0.83 | HTT (0.71) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL17117306 | 0.83 | EPHX2 (1.00) | HTTEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL13585258 | 0.82 | HTT (0.69) | HTTEPHX2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | claimed |
| EP-2048951-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-22 | — | — | EP | claimed |
| WO-2008017816-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | claimed |
| US-8178567-B2 | Insecticidal substituted amino heterocyclic and heteroaryl derivatives | FMC CORPORATION (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100137385-A1 | Insecticidal Substituted Amino Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| EP-2048951-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008017816-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137385-A1 | Insecticidal Substituted Amino Heterocyclic and Heteroaryl Derivatives | DDT, AAAS, DDC | HTT 2010/4885EPHX2 391/4885ALDH1A1 1398/4885 |
| US-20100280085-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, COX6B1 | HTT 2263/4885EPHX2 585/4885ALDH1A1 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.