Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014048 | 0.88 | TRPV1 (0.49) | TRPV1EPHX2HTTPDE10ADHODH | |
| SCHEMBL3731433 | 0.82 | EPHX2 (0.69) | EPHX2HTTDHODHKMT2AALDH1A1 | |
| SCHEMBL4710669 | 0.78 | CA12 (0.57) | TRPV1PDE10AKMT2ALMNAMEN1 | |
| SCHEMBL4014154 | 0.78 | TRPV1 (0.50) | TRPV1EPHX2HTTPDE10ADHODH | |
| SCHEMBL4017010 | 0.75 | TRPV1 (0.48) | TRPV1EPHX2HTTDHODHLMNA | |
| SCHEMBL3735037 | 0.74 | HTT (0.77) | EPHX2HTTDHODHKMT2AALDH1A1 | |
| SCHEMBL4017499 | 0.73 | EPHX2 (0.49) | TRPV1EPHX2HTTPDE10ADHODH | |
| SCHEMBL4017836 | 0.72 | EPHX2 (0.48) | TRPV1EPHX2HTTKMT2ALMNA | |
| SCHEMBL4017021 | 0.72 | MTNR1A (0.54) | PDE10A | |
| SCHEMBL23362760 | 0.72 | TRPV1 (0.43) | TRPV1PDE10AKMT2AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| EP-2048951-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008017816-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008017816-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280085-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, COX6B1 | TRPV1 474/4885EPHX2 585/4885HTT 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.