Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198158 | 0.85 | ALDH1A1 (0.67) | HTTATMGAAMAPK1ALDH1A1 | |
| SCHEMBL2197478 | 0.85 | ALDH1A1 (0.67) | HTTATMGAAMAPK1ALDH1A1 | |
| SCHEMBL3728952 | 0.78 | ATM (0.57) | HTTATMGAAALDH1A1HPGD | |
| SCHEMBL3727127 | 0.76 | ALDH1A1 (0.56) | HTTATMGAAMAPK1ALDH1A1 | |
| SCHEMBL3729367 | 0.75 | ATM (1.00) | HTTATMALDH1A1MEN1KMT2A | |
| SCHEMBL11887696 | 0.74 | GAA (1.00) | GAAMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL29887392 | 0.74 | GAA (1.00) | GAAMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL6740216 | 0.73 | TAAR1 (0.71) | KMT2ATAAR1 | |
| SCHEMBL17967124 | 0.72 | ALDH1A1 (0.72) | HTTATMGAAALDH1A1MEN1 | |
| SCHEMBL3729052 | 0.71 | HTT (0.74) | HTTGAAMAPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | HTT 3634/4885ATM 3093/4885GAA 735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.