Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 10/20 | 0.40 |
| ▸ | GRM6 | O15303 | 8/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.40 |
| ▸ | GRM5 | P41594 | 5/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202772 | 1.00 | SLC6A4 (0.41) | SLC6A4GRM2GRM6GRM4GRM5 | |
| SCHEMBL26746340 | 1.00 | SLC6A4 (0.41) | SLC6A4GRM2GRM6GRM4GRM5 | |
| Water SCHEMBL10753838 | 0.98 | SLC6A4 (0.40) | SLC6A4GRM2GRM6GRM4GRM5 | |
| Water SCHEMBL10753833 | 0.98 | SLC6A4 (0.40) | SLC6A4GRM2GRM6GRM4GRM5 | |
| SCHEMBL22582250 | 0.87 | GRM2 (0.47) | SLC6A4GRM2GRM6GRM4GRM5 | |
| SCHEMBL8663610 | 0.85 | THRB (0.48) | SLC6A4GRM2GRM6GRM4GRM5 | |
| SCHEMBL2009762 | 0.83 | THRB (0.35) | THRBCYP2C9HSD11B1 | |
| SCHEMBL9457723 | 0.83 | THRB (0.35) | THRBCYP2C9HSD11B1 | |
| SCHEMBL7976925 | 0.82 | GRM2 (0.43) | SLC6A4GRM2GRM6GRM4GRM5 | |
| SCHEMBL26747648 | 0.82 | SLC1A2 (0.37) | THRBCYP2C9HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722014-B2 | 1 H-[1, 2, 3] triazole substituted amino acids and uses thereof | WASHINGTON UNIVERSITY (US) | 2014-05-13 | — | — | US | disclosed |
| US-20100278732-A1 | 1H-[1, 2, 3] TRIAZOLE SUBSTITUTED AMINO ACIDS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278732-A1 | 1H-[1, 2, 3] TRIAZOLE SUBSTITUTED AMINO ACIDS AND USES THEREOF | SLC7A1, SLC1A5, SLC1A3 | SLC6A4 40/4885GRM2 1187/4885GRM6 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.