Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437187 | 0.78 | HTT (0.45) | HTTEPHX2ALDH1A1EPHX1NPC1 | |
| SCHEMBL3735037 | 0.73 | HTT (0.77) | HTTEPHX2ALDH1A1EPHX1DHODH | |
| SCHEMBL3731433 | 0.73 | EPHX2 (0.69) | HTTEPHX2ALDH1A1EPHX1DHODH | |
| SCHEMBL3735803 | 0.71 | NPC1 (0.53) | HTTEPHX2NPC1 | |
| SCHEMBL10699741 | 0.70 | PTGDR2 (0.42) | HTTALDH1A1PPIAHPGD | |
| SCHEMBL3738300 | 0.68 | HTT (0.39) | HTTEPHX2ALDH1A1EPHX1TSHR | |
| SCHEMBL10407023 | 0.68 | PTGDR2 (0.36) | HTTEPHX2ALDH1A1HPGDTAS1R3 | |
| SCHEMBL8670897 | 0.67 | PPIA (0.58) | TSHRPPIA | |
| SCHEMBL6369376 | 0.67 | EPHX2 (0.46) | HTTEPHX2ALDH1A1DHODHPPIA | |
| SCHEMBL13984230 | 0.67 | TRPV1 (0.51) | HTTEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | claimed |
| EP-2048951-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-22 | — | — | EP | claimed |
| WO-2008017816-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | claimed |
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| EP-2048951-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008017816-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280085-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, COX6B1 | HTT 2263/4885EPHX2 585/4885ALDH1A1 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.