⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358736 | 0.92 | TRIM24 (0.35) | — | |
| SCHEMBL1944461 | 0.86 | — | — | |
| SCHEMBL9778790 | 0.76 | — | — | |
| SCHEMBL27412225 | 0.76 | — | — | |
| SCHEMBL28152876 | 0.74 | BRD4 (0.31) | — | |
| SCHEMBL37337 | 0.72 | — | — | |
| SCHEMBL2564447 | 0.71 | USP2 (0.33) | — | |
| SCHEMBL2148745 | 0.71 | — | — | |
| SCHEMBL16380350 | 0.70 | LMNA (0.33) | — | |
| SCHEMBL27488043 | 0.70 | KCNQ2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2930176-A1 | HYDANTOIN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2015-10-14 | — | — | EP | disclosed |
| WO-2008033299-A2 | USE OF N-CONTAINING SPIROCOMPOUNDS FOR THE ENHANCEMENT OF COGNITIVE FUNCTION | ADOLOR CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |
| US-6683095-B2 | ANTICARCINOGENIC AGENTS; ANTIPROLIFERATION AGENTS | LG LIFE SCIENCES LTD. (KR) | 2004-01-27 | — | — | US | disclosed |
| US-20030125356-A1 | Cdk inhibitors having 3-hydroxychromen-4-one structure | LG LIFE SCIENCES LTD. (KR) | 2003-07-03 | — | — | US | disclosed |
| EP-1224180-B1 | SUBSTITUTED AZOLES | NOVARTIS AG (CH) | 2003-07-02 | — | — | EP | disclosed |
| US-6579874-B2 | P38 MAP kinase inhibitors; treating Tumor necrosis factor (TNF-alpha) and Interleukin-1 mediated diseases, such as rheumatoid arthritis; imidazole and oxazole derivatives | NOVARTIS AG (CH) | 2003-06-17 | — | — | US | disclosed |
| CN-1098259-C | Novel carboxy-substituted cyclic carboxamide derivatives | AVENTIS PHARMA INC (US) | 2003-01-08 | — | — | CN | disclosed |
| EP-1224180-A2 | SUBSTITUTED AZOLES | Novartis AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| US-20020049220-A1 | Substituted azoles | NOVARTIS AG (CH) | 2002-04-25 | — | — | US | disclosed |
| WO-2000063204-A2 | SUBSTITUTED AZOLES | NOVARTIS AG (CH) | 2000-10-26 | — | — | WO | disclosed |
| CN-1240443-A | Novel carboxy substituted cyclic carboxamide derivatives | HOECHST MARION ROUSSEL INC (US) | 2000-01-05 | — | — | CN | disclosed |