Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436320 | 0.87 | CA12 (0.49) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL3737684 | 0.84 | CA12 (0.53) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL3728433 | 0.83 | KAT2B (0.45) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1052760 | 0.80 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1052536 | 0.79 | KAT2B (0.47) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1052534 | 0.79 | CA12 (0.47) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1052583 | 0.77 | KAT2B (0.42) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL9688318 | 0.77 | CA12 (0.53) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL3738350 | 0.76 | KAT2B (0.41) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1055086 | 0.76 | KDM4E (0.45) | CA12CA9BRD4BRPF1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825132-B2 | Inhibition of FGFR3 and treatment of multiple myeloma | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-11-02 | — | — | US | disclosed |