Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436320 | 0.83 | CA12 (0.49) | KAT2BCA12BRD4BRPF1CA9 | |
| SCHEMBL3733975 | 0.83 | CA12 (0.49) | KAT2BCA12BRD4BRPF1CA9 | |
| SCHEMBL3737684 | 0.80 | CA12 (0.53) | KAT2BCA12BRD4BRPF1CA9 | |
| SCHEMBL1052536 | 0.75 | KAT2B (0.47) | KAT2BCA12BRD4BRPF1CA9 | |
| SCHEMBL1052534 | 0.75 | CA12 (0.47) | KAT2BCA12BRD4BRPF1CA9 | |
| SCHEMBL1052583 | 0.74 | KAT2B (0.42) | KAT2BCA12BRD4BRPF1CA9 | |
| SCHEMBL1052760 | 0.73 | CA12 (0.57) | KAT2BCA12BRD4BRPF1CA9 | |
| SCHEMBL3738350 | 0.72 | KAT2B (0.41) | KAT2BCA12BRD4BRPF1CA9 | |
| SCHEMBL1055086 | 0.72 | KDM4E (0.45) | KAT2BCA12BRD4BRPF1CA9 | |
| SCHEMBL3731044 | 0.71 | HRH3 (0.49) | CYP2C19ALDH1A1CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825132-B2 | Inhibition of FGFR3 and treatment of multiple myeloma | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-11-02 | — | — | US | disclosed |