Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3737684 | 0.88 | CA12 (0.53) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL3733975 | 0.87 | CA12 (0.49) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL3728433 | 0.83 | KAT2B (0.45) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1052536 | 0.79 | KAT2B (0.47) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1052534 | 0.79 | CA12 (0.47) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1052583 | 0.77 | KAT2B (0.42) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1052760 | 0.77 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL3738350 | 0.76 | KAT2B (0.41) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1055086 | 0.76 | KDM4E (0.45) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL3731044 | 0.75 | HRH3 (0.49) | KMT2AALDH1A1LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112794818-A | Preparation method of N-propylaminoquinolinone and application of N-propylaminoquinolinone in synthesis of abscisic acid agonist AM1 and derivatives thereof | 邵阳学院 | 2021-05-14 | — | — | CN | disclosed |
| EP-1560827-A1 | ANTI-INFECTIVE AGENTS | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041818-A1 | ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-05-21 | — | — | WO | disclosed |