Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 20/20 | 1.00 |
| ▸ | MAPK14 | Q16539 | 5/20 | 1.00 |
| ▸ | THRB | P10828 | 4/20 | 1.00 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.62 |
| ▸ | GAK | O14976 | 1/20 | 0.62 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.62 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.62 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.62 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.62 |
| ▸ | TGFB2 | P61812 | 1/20 | 0.62 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.62 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.62 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.62 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412988 | 0.93 | TGFBR1 (0.87) | TGFBR1MAPK14THRBTGFBR2GAK | |
| SCHEMBL410580 | 0.91 | TGFBR1 (0.84) | TGFBR1MAPK14THRBTGFBR2GAK | |
| SCHEMBL414746 | 0.91 | TGFBR1 (0.83) | TGFBR1MAPK14THRBTGFBR2GAK | |
| SCHEMBL414737 | 0.90 | TGFBR1 (0.82) | TGFBR1MAPK14THRBTGFBR2GAK | |
| SCHEMBL413831 | 0.90 | TGFBR1 (0.81) | TGFBR1MAPK14THRBTGFBR2GAK | |
| SCHEMBL414312 | 0.89 | TGFBR1 (0.80) | TGFBR1MAPK14THRBTGFBR2GAK | |
| SCHEMBL413269 | 0.88 | TGFBR1 (0.79) | TGFBR1MAPK14THRBTGFBR2GAK | |
| SCHEMBL414844 | 0.88 | TGFBR1 (0.78) | TGFBR1MAPK14THRBTGFBR2GAK | |
| SCHEMBL411939 | 0.88 | TGFBR1 (0.78) | TGFBR1MAPK14THRBTGFBR2GAK | |
| SCHEMBL5239595 | 0.87 | TGFBR1 (0.77) | TGFBR1MAPK14THRBTGFBR2GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871744-B2 | Compounds and methods for selectively targeting tumor-associated mucins | B & G Partyers, LLC (US) | 2014-10-28 | — | — | US | disclosed |
| US-20120022016-A1 | Compounds and methods for selectively targeting tumor-associated mucins | B&G PARTNERS, LLC | 2012-01-26 | — | — | US | disclosed |
| EP-2409708-A1 | Compounds and methods for selectively targeting tumor-associated mucins | B & G Partners, LLC (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-1397364-B1 | NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | LILLY CO ELI (US) | 2007-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022016-A1 | Compounds and methods for selectively targeting tumor-associated mucins | MUC1, NEU4, ALK | TGFBR1 1324/4885MAPK14 2025/4885THRB 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.