SCHEMBL373532

SCHEMBL373532

CCC[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14595042 0.94
SCHEMBL373448 0.87
SCHEMBL12288165 0.86
SCHEMBL17123473 0.84
SCHEMBL14981945 0.84
SCHEMBL18017227 0.84
SCHEMBL860349 0.83
SCHEMBL373996 0.82 ADRB2 (0.33)
SCHEMBL15961083 0.82
SCHEMBL1002365 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022135873-A1 COMPONENT, ELECTROCHEMICAL CELL AND METHOD FOR PRODUCING A COMPONENT ELRINGKLINGER AG (DE) 2022-06-30 WO claimed
EP-2648896-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES Novartis AG (CH) 2013-10-16 EP claimed
EP-2598937-A2 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF Novartis AG (CH) 2013-06-05 EP claimed
WO-2012078457-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2012-06-14 WO claimed
WO-2012016097-A2 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2012-02-02 WO claimed
US-20050069564-A1 Use of siloxanes as evaporable supports MOMENTIVE PERFORMANCE MATERIALS INC. 2005-03-31 US claimed
EP-1472263-A1 USE OF SILOXANES AS EVAPORABLE SUPPORTS GE Bayer Silicones GmbH &amp; Co. KG (DE) 2004-11-03 EP claimed
WO-2003042221-A1 USE OF SILOXANES AS EVAPORABLE SUPPORTS GE BAYER SILICONES GMBH & CO. KG (DE) 2003-05-22 WO claimed
US-20240238188-A1 OILY COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-18 US disclosed
EP-4313568-A1 EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-02-07 EP disclosed
US-20230203360-A1 Paste VALQUA LTD (JP) 2023-06-29 US disclosed
EP-3890951-A1 METHOD FOR COATED SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2021-10-13 EP disclosed
EP-3570093-B1 CONTACT LENS WITH A HYDROPHILIC LAYER TANGIBLE SCIENCE INC (US) 2021-09-15 EP disclosed
EP-3759528-A1 SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2021-01-06 EP disclosed
EP-0715637-A1 SILICONE GRAFTED THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1996-06-12 EP disclosed
EP-0706537-A1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1996-04-17 EP disclosed
WO-1995001384-A1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1995-01-12 WO disclosed
EP-0236914-B1 FABRICATION OF ELECTRONIC DEVICES UTILIZING LITHOGRAPHIC TECHNIQUES AT&T Corp. (US) 1990-03-14 EP disclosed
US-4701342-A COPOLYMERS FROM TRIALKYLSILYLALKYL METHACRYLATE AND HALOGENATED STYRENE DERIVATIVES OR HALOGENATED VINYL NAPHTHALENE DERIVATIVES AMERICAN TELEPHONE AND TELEGRAPH COMPANY, AT&T BELL LABORATORIES (US) 1987-10-20 US disclosed
EP-0236914-A2 Fabrication of electronic devices utilizing lithographic techniques AT&T Corp. (US) 1987-09-16 EP disclosed