Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3725813 | 0.99 | TACR1 (0.49) | TACR1GHSRSLC6A4SLC6A2ADRB1 | |
| SCHEMBL3731664 | 0.88 | GHSR (0.63) | TACR1GHSRSLC6A4 | |
| Hydrochloric Acid SCHEMBL3728776 | 0.87 | GHSR (0.62) | TACR1GHSRSLC6A4 | |
| SCHEMBL3808867 | 0.81 | ADRB1 (0.37) | TACR1SLC6A4ADRB1 | |
| SCHEMBL3667305 | 0.80 | GHSR (0.47) | TACR1GHSR | |
| SCHEMBL3666028 | 0.80 | GHSR (0.47) | TACR1GHSR | |
| SCHEMBL3638174 | 0.78 | GHSR (0.78) | TACR1GHSR | |
| Hydrochloric Acid SCHEMBL3746485 | 0.77 | GHSR (0.77) | TACR1GHSR | |
| SCHEMBL4557810 | 0.73 | RXFP1 (0.47) | TACR1SLC6A4SLC6A2ADRB1RXFP1 | |
| SCHEMBL14593402 | 0.73 | RXFP1 (0.47) | TACR1SLC6A4SLC6A2ADRB1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |