Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1210670 | 0.86 | DAO (0.62) | DAORIPK1HRH4HRH3AURKA | |
| SCHEMBL30549017 | 0.83 | DAO (0.59) | DAORIPK1KDM4ETDP1ALDH1A1 | |
| SCHEMBL1219236 | 0.82 | EGLN1 (0.55) | DAORIPK1MAPTGAA | |
| SCHEMBL253780 | 0.79 | ALDH1A1 (0.54) | DAORIPK1KDM4EALDH1A1MAPT | |
| SCHEMBL28569929 | 0.79 | EGLN1 (0.55) | DAOKDM4ETDP1ALDH1A1TSHR | |
| SCHEMBL3714541 | 0.78 | DAO (1.00) | DAORIPK1AURKAPARP1 | |
| SCHEMBL296469 | 0.78 | HRH4 (0.57) | DAORIPK1KDM4EALDH1A1HRH4 | |
| SCHEMBL5677159 | 0.77 | DAO (0.59) | DAORIPK1KDM4EALDH1A1HRH4 | |
| Quinoline SCHEMBL11495860 | 0.77 | PADI4 (0.50) | DAOKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL31143182 | 0.77 | DAO (0.55) | DAORIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527288-A | Process for preparing quinolone-or naphthyridonecarboxylic acid derivatives | 沈阳药科大学 | 2021-10-22 | — | — | CN | claimed |
| CN-102180874-A | Synthetic process method for azabicyclo medicinal intermediates | ACCELA CHEMBIO INC | 2011-09-14 | — | — | CN | claimed |
| CN-102101861-A | Synthesis and process method of nitrogen-containing bis-heterocyclic medicine intermediate | ACCELA CHEMBIO CO LTD | 2011-06-22 | — | — | CN | claimed |
| EP-1355629-B1 | SOLID PHASE DISPERSION OF QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACIDS | BAYER HEALTHCARE LLC (US) | 2008-10-01 | — | — | EP | claimed |
| US-7175856-B2 | Palatable oral suspension and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-13 | — | — | US | claimed |
| US-7112336-B2 | Solid phase dispersion of quinolone or naphthyridonecarboxylic acids | BAYER HEALTHCARE LLC (US) | 2006-09-26 | — | — | US | claimed |
| US-20050118205-A1 | Taste masked liquid pharmaceutical compositions | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-06-02 | — | — | US | claimed |
| EP-1482789-A2 | PALATABLE ORAL SUSPENSION AND METHOD | Bristol-Myers Squibb Company (US) | 2004-12-08 | — | — | EP | claimed |
| US-20040204442-A1 | Solid phase dispersion of quinolone or naphthyridonecarboxylic acids | BAYER PHARMACEUTICALS CORPORATION | 2004-10-14 | — | — | US | claimed |
| US-6767557-B2 | Taste masked pharmaceutical compositions | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-07-27 | — | — | US | claimed |
| EP-0858357-B1 | METHODS FOR DECOMPOSING QUINOLONES AND NAPHTHYRIDONES | BAYER AG (DE) | 1999-06-09 | — | — | EP | claimed |
| CN-1200678-A | Method for degrading quinolones and naphthyridones | BAYER AG (DE) | 1998-12-02 | — | — | CN | claimed |
| US-5811433-A | ANTIMICROBIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-22 | — | — | US | claimed |
| US-5808076-A | BACTERICIDES; MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | claimed |
| CN-1185786-A | Sugar-modified cytostatics | BAYER AG (DE) | 1998-06-24 | — | — | CN | claimed |
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | claimed |
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | claimed |
| EP-0221493-B1 | Use of gyrase blocking agents in decontaminating cell cultures infested by mycoplasmas | BAYER AG (DE) | 1994-05-25 | — | — | EP | claimed |
| CN-87100354-A | Derivatives of 7- (azabicycloalkyl) -quinolone-and 7- (azabicycloalkyl) -naphthyridonecarboxylic acids | — | 1987-09-02 | — | — | CN | claimed |
| EP-0049355-B1 | 7-Amino-1-cyclopropyl-4-oxo-1,4-dihydro-(naphthyridine or quinoline)-3-carboxylic acids, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1984-10-10 | — | — | EP | claimed |