Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22185856 | 0.81 | DAO (0.61) | DAOKDM4ERIPK1ALDH1A1HPGD | |
| SCHEMBL13906225 | 0.80 | DAO (0.59) | DAOKDM4ERIPK1ALDH1A1HPGD | |
| SCHEMBL29587495 | 0.80 | DAO (0.51) | DAORIPK1HRH4HRH3 | |
| SCHEMBL833073 | 0.80 | DAO (0.59) | DAOKDM4ERIPK1ALDH1A1HPGD | |
| SCHEMBL373592 | 0.77 | DAO (0.64) | DAOKDM4EMAPTRIPK1ALDH1A1 | |
| SCHEMBL5676880 | 0.77 | KDM4E (0.43) | KDM4ECYP1A2ALDH1A1KMT2AHPGD | |
| SCHEMBL5676978 | 0.77 | HRH4 (0.39) | EGLN1KDM4ECYP1A2PTGDR2ALDH1A1 | |
| SCHEMBL5677293 | 0.75 | EGLN1 (0.40) | EGLN1KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL5678790 | 0.75 | MAPK1 (0.61) | DAOKDM4ECYP1A2ALDH1A1MEN1 | |
| SCHEMBL30434363 | 0.75 | MAPK1 (0.61) | DAOKDM4ECYP1A2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988045-B1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NIELSEN PETER EIGIL (DK) | 2006-02-08 | — | — | EP | disclosed |
| US-6632919-B1 | Bind Watson-Crick base pairs in a double helix; specific for thymidine | Nielsen, Peter (DK) | 2003-10-14 | — | — | US | disclosed |
| US-6617422-B1 | Of given formula; stronger binding and greater specificity than oligonucleotides; useful as probes in cloning, blotting procedures, and in applications such as fluorescence in situ hybridization; can use to detect point mutations | Nielsen, Peter (DK) | 2003-09-09 | — | — | US | disclosed |