Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.69 |
| ▸ | GNB1 | P62873 | 5/20 | 0.69 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.68 |
| ▸ | P2RY4 | P51582 | 10/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.56 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.54 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.54 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303602 | 0.91 | GNG2 (0.58) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL4298127 | 0.91 | CHAT (0.67) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL8402397 | 0.90 | PHLPP2 (0.84) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL1592192 | 0.89 | PHLPP2 (0.67) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL11311121 | 0.89 | PHLPP2 (0.82) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL374031 | 0.86 | PHLPP2 (0.55) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL11119697 | 0.85 | GNG2 (0.70) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL14379194 | 0.85 | GNG2 (0.70) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL11502964 | 0.84 | GNG2 (0.71) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL27995224 | 0.83 | GNG2 (0.67) | GNG2GNB1PHLPP2P2RY4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068316-A1 | MATERIAL FOR SOFT CONTACT LENS HAVING CONTRAST IMPROVEMENT FUNCTION | 興和株式会社 | 2023-04-27 | — | — | WO | disclosed |
| US-20210163650-A1 | POLYMER MATERIAL | MENICON CO., LTD. (JP) | 2021-06-03 | — | — | US | disclosed |
| EP-3822296-A1 | POLYMER MATERIAL | Menicon Co., Ltd. (JP) | 2021-05-19 | — | — | EP | disclosed |
| EP-3086162-B1 | OCULAR LENS | MENICON CO LTD (JP) | 2019-04-17 | — | — | EP | disclosed |
| US-20180356561-A1 | GEL, GEL MANUFACTURING METHOD, LENS, CONTACT LENS SURFACE MODIFIER, POLYMERIZABLE COMPOSITION, AND POLYMER | JSR CORPORATION (JP) | 2018-12-13 | — | — | US | disclosed |
| EP-3086163-B1 | POLYSILOXANE-BASED MACROMONOMER FOR USE IN OCULAR LENS AND OCULAR LENS USING SAME | MENICON CO LTD (JP) | 2018-11-14 | — | — | EP | disclosed |
| EP-2857459-B1 | STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS | KOWA CO (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-9657131-B2 | Ophthalmic lens | MENICON CO., LTD. (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9650473-B2 | Polysiloxane-based macromonomer for ophthalmic lens and ophthalmic lens using the same | MENICON CO., LTD. (JP) | 2017-05-16 | — | — | US | disclosed |
| EP-3086163-A1 | POLYSILOXANE-BASED MACROMONOMER FOR USE IN OCULAR LENS AND OCULAR LENS USING SAME | Menicon Co., Ltd. (JP) | 2016-10-26 | — | — | EP | disclosed |
| US-5416180-A | Fluorine containing (meth)acrylate polymers | MENICON CO., LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0381005-B1 | Ocular lens material | MENICON CO LTD (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-5346946-A | Polysiloxane macromonomer | MENICON CO., LTD (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0600269-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1994-06-08 | — | — | EP | disclosed |
| EP-0584826-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0584764-A1 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0578087-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5041511-A | Vinyl benzene acrylate or methacrylate crosslinking agent | MENICON CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| US-4954586-A | COPOLYMER OF A FLUORINE CONTAINING (METH)ACRYLATE, AN ALKYL (METH)ACRYLATE, A POLYSILOXANE AND A URETHANE CONTAINING POLYSILOXANE | MENICON CO., LTD (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0381005-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1990-08-08 | — | — | EP | disclosed |