Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.58 |
| ▸ | GNB1 | P62873 | 5/20 | 0.58 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.58 |
| ▸ | CHAT | P28329 | 4/20 | 0.57 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.57 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.57 |
| ▸ | P2RY4 | P51582 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4298127 | 0.93 | CHAT (0.67) | GNG2GNB1PHLPP2CHATENPP3 | |
| SCHEMBL373603 | 0.91 | GNG2 (0.69) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL7755289 | 0.82 | CHAT (0.76) | GNG2GNB1PHLPP2CHATENPP3 | |
| SCHEMBL8402397 | 0.82 | PHLPP2 (0.84) | GNG2GNB1PHLPP2CHATENPP3 | |
| SCHEMBL1592192 | 0.81 | PHLPP2 (0.67) | GNG2GNB1PHLPP2CHATENPP3 | |
| SCHEMBL11311121 | 0.81 | PHLPP2 (0.82) | GNG2GNB1PHLPP2CHATENPP3 | |
| SCHEMBL25220147 | 0.79 | P2RY4 (0.80) | GNG2GNB1PHLPP2CHATENPP3 | |
| SCHEMBL30392069 | 0.79 | P2RY4 (0.80) | GNG2GNB1PHLPP2CHATENPP3 | |
| SCHEMBL374031 | 0.78 | PHLPP2 (0.55) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL14379194 | 0.78 | GNG2 (0.70) | GNG2GNB1PHLPP2P2RY4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163650-A1 | POLYMER MATERIAL | MENICON CO., LTD. (JP) | 2021-06-03 | — | — | US | disclosed |
| EP-3822296-A1 | POLYMER MATERIAL | Menicon Co., Ltd. (JP) | 2021-05-19 | — | — | EP | disclosed |
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| EP-2581394-A1 | IONIC COMPOUND, COMPOSITION, CURED PRODUCT, HYDROGEL, AND OCULAR LENS | Menicon Co., Ltd. (JP) | 2013-04-17 | — | — | EP | disclosed |
| EP-1696257-B1 | CONTACT LENS MATERIAL | MENICON CO LTD (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20090247662-A1 | Contact Lens Material | MATSUMOTO MASAHIRO | 2009-10-01 | — | — | US | disclosed |
| EP-1033590-B1 | Ocular lens material | MENICON CO LTD (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20070149699-A1 | Contact lens material | MENICON CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1696257-A1 | CONTACT LENS MATERIAL | MENICON CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6329445-B1 | Ocular lens material | MENICON CO., LTD (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1033590-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 2000-09-06 | — | — | EP | disclosed |
| EP-0947856-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1999-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | CRYZ, CRYAA, VIL1 | GNG2 1251/4885GNB1 1242/4885PHLPP2 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.