SCHEMBL3736586

SCHEMBL3736586

O=C(O)Cc1c(F)ccc(Cl)c1F

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.52
KDM4E B2RXH2 1/20 0.42
GPR17 Q13304 1/20 0.40
CA2 P00918 1/20 0.38
SLC22A12 Q96S37 2/20 0.38
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
PTGDR2 Q9Y5Y4 2/20 0.37
PTGDR Q13258 1/20 0.37
CXCL8 P10145 1/20 0.36
CYP2C9 P11712 1/20 0.36
CD38 P28907 1/20 0.36
FABP4 P15090 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30812814 0.85 AKR1B1 (0.57) AKR1B1KDM4EGPR17CA2LMNA
SCHEMBL18301609 0.85 AKR1B1 (0.52) AKR1B1KDM4EGPR17CA2LMNA
SCHEMBL18301625 0.85 AKR1B1 (0.57) AKR1B1KDM4EGPR17CA2LMNA
SCHEMBL29459948 0.84 AKR1B1 (0.43) AKR1B1KDM4ECA2LMNASMN1; SMN2
SCHEMBL909585 0.84 AKR1B1 (0.43) AKR1B1KDM4ECA2LMNASMN1; SMN2
Hydrochloric Acid SCHEMBL1372127 0.82 AKR1B1 (0.42) AKR1B1KDM4ECA2LMNASMN1; SMN2
SCHEMBL22031847 0.81 AKR1B1 (0.48) AKR1B1KDM4ECA2LMNASMN1; SMN2
SCHEMBL29457633 0.81 AKR1B1 (0.48) AKR1B1KDM4ECA2LMNASMN1; SMN2
SCHEMBL19522398 0.81 GPR17 (0.55) KDM4EGPR17
SCHEMBL12709973 0.80 TSHR (0.41) KDM4ESMN1; SMN2MAPTKMT2ACD38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3114715-B1 P-DOPING CROSS-LINKING OF ORGANIC HOLE TRANSPORTERS SIEMENS AG (DE) 2019-10-30 EP claimed
EP-3114715-A1 P-DOPING CROSS-LINKING OF ORGANIC HOLE TRANSPORTERS Siemens Aktiengesellschaft (DE) 2017-01-11 EP claimed
US-20250185502-A1 ORGANIC OPTOELECTRONIC COMPONENT, ORGANIC FUNCTIONAL LAYER, AND METHOD FOR PRODUCING AN OPTOELECTRONIC COMPONENT OSRAM OLED GMBH (DE) 2025-06-05 US disclosed
US-12302747-B2 Optoelectronic component, organic functional layer, and method for producing an optoelectronic component OSRAM OLED GMBH (DE) 2025-05-13 US disclosed
EP-4193399-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2025-01-29 EP disclosed
EP-3210248-B2 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-04-10 EP disclosed
EP-4193399-A2 ELECTRONIC DEVICE Merck Patent GmbH (DE) 2023-06-14 EP disclosed
CN-116194434-A Electronic device 默克专利有限公司 2023-05-30 CN disclosed
CN-107074797-B Material for electronic devices 默克专利有限公司 2022-04-15 CN disclosed
US-11038127-B2 Optoelectronic component, organic functional layer, and method for producing an optoelectronic component OSRAM OLED GMBH (DE) 2021-06-15 US disclosed
EP-3298639-B1 FORMULATION CONTAINING AN ORGANIC SEMICONDUCTOR AND A METAL COMPLEX MERCK PATENT GMBH (DE) 2021-01-13 EP disclosed
US-20150266870-A1 MULTIPLE KINASE PATHWAY INHIBITORS MANNKIND CORPORATION 2015-09-24 US disclosed
US-20150162534-A1 METAL COMPLEXES AS P-TYPE DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS OSRAM OLED GMBH (DE) 2015-06-11 US disclosed
US-20150123047-A1 MAIN GROUP METAL COMPLEXES AS P-DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS OSRAM OLED GMBH (DE) 2015-05-07 US disclosed
US-7829567-B2 Imino-indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same KAOHSIUNG MEDICAL UNIVERSITY (TW) 2010-11-09 US disclosed
US-20090111987-A1 Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same KAOHSIUNG MEDICAL UNIVERSITY (TW) 2009-04-30 US disclosed
EP-1314725-B1 SULFONIUM SALT COMPOUND WAKO PURE CHEM IND LTD (JP) 2008-03-19 EP disclosed
US-6924323-B2 Sulfonium salt compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 US disclosed
US-20040033434-A1 Sulfonium salt compound FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2004-02-19 US disclosed
EP-1314725-A1 SULFONIUM SALT COMPOUND Wako Pure Chemical Industries, Ltd. (JP) 2003-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266870-A1 MULTIPLE KINASE PATHWAY INHIBITORS MAP3K6, MAP3K2, MAP3K1 AKR1B1 3456/4885KDM4E 2130/4885GPR17 4058/4885
US-20090111987-A1 Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same IMPA1, IMPDH1, IPO5 AKR1B1 2359/4885KDM4E 1726/4885GPR17 3656/4885
US-20040033434-A1 Sulfonium salt compound SPIN1, RER1, SPIN2B AKR1B1 3105/4885KDM4E 1259/4885GPR17 2596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.