SCHEMBL29429645

SCHEMBL29429645

O=C(O)[C@H](Cc1ccc(O)c(O)c1)NO

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.62
KDM4E B2RXH2 7/20 0.60
HSD17B10 Q99714 6/20 0.60
TDP1 Q9NUW8 6/20 0.60
RECQL P46063 5/20 0.60
ALOX15 P16050 4/20 0.60
HIF1A Q16665 4/20 0.60
USP2 O75604 3/20 0.60
LCK P06239 3/20 0.60
ADORA3 P0DMS8 2/20 0.60
HTR2A P28223 2/20 0.60
PTGS2 P35354 2/20 0.60
FYN P06241 2/20 0.60
EGFR P00533 1/20 0.60
PTGS1 P23219 1/20 0.60
SLC7A5 Q01650 1/20 0.60
CA1 P00915 4/20 0.56
CA2 P00918 4/20 0.56
MME P08473 1/20 0.53
ACE P12821 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5063603 1.00 KDM6B (0.62) KDM6BKDM4EHSD17B10TDP1RECQL
SCHEMBL30724831 0.88 KDM6B (0.64) KDM6BKDM4EHSD17B10TDP1RECQL
Levodopa SCHEMBL4551885 0.86 SLC7A5 (0.69) KDM6BKDM4EHSD17B10TDP1RECQL
SCHEMBL29669984 0.86 KDM6B (0.62) KDM6BKDM4EHSD17B10TDP1RECQL
SCHEMBL1828829 0.85 ESR1 (0.49) KDM6BKDM4EHSD17B10TDP1RECQL
SCHEMBL1828830 0.85 ESR1 (0.49) KDM6BKDM4EHSD17B10TDP1RECQL
SCHEMBL2283369 0.85 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1RECQL
SCHEMBL3736877 0.85 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1RECQL
SCHEMBL32662363 0.85 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1RECQL
SCHEMBL18800390 0.85 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127167-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-04-24 US claimed
CN-119752091-A ABS composite material containing halogen-free flame retardant and preparation process thereof 东莞市宇捷实业投资有限公司 2025-04-04 CN claimed
EP-4401555-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2024-07-24 EP claimed
CN-117820374-A DOPO-based Schiff base derivative halogen-free flame retardant, and preparation method and application thereof 浙江理工大学 2024-04-05 CN claimed
WO-2023042201-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-03-23 WO claimed
US-12397060-B2 pHLIP®-mediated intracellular delivery of immuno-stimulatory compounds UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2025-08-26 US disclosed
CN-119752091-B ABS composite material containing halogen-free flame retardant and preparation process thereof 东莞市宇捷实业投资有限公司 2025-07-15 CN disclosed
US-12290575-B2 Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2025-05-06 US disclosed
US-20250127167-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-04-24 US disclosed
CN-119752091-A ABS composite material containing halogen-free flame retardant and preparation process thereof 东莞市宇捷实业投资有限公司 2025-04-04 CN disclosed
CN-119752091-A ABS composite material containing halogen-free flame retardant and preparation process thereof 东莞市宇捷实业投资有限公司 2025-04-04 CN disclosed
CN-114965764-B Diagnosis and treatment of constipation 陕西安宁云生生物技术有限公司 2024-12-31 CN disclosed
US-11738096-B2 Method of detecting diseased or damaged tissue with a pH-triggered polypeptide fluorophore composition YALE UNIVERSITY (US) 2023-08-29 US disclosed
US-11723897-B2 Fatty acids as anti-inflammatory agents University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2023-08-15 US disclosed
WO-2023042201-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-03-23 WO disclosed
WO-2022229951-A1 ANTIMICROBIAL AGENTS AND FILMS MADE THEREFROM YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2022-11-03 WO disclosed
WO-2022224247-A1 ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2022-10-27 WO disclosed
CN-114965764-A Diagnosis and treatment of constipation 陕西安宁云生生物技术有限公司 2022-08-30 CN disclosed
US-20220088208-A1 PHLIP®-MEDIATED INTRACELLULAR DELIVERY OF IMMUNO-STIMULATORY COMPOUNDS UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2022-03-24 US disclosed
US-11267853-B2 Carbohydrate tethering at cell surfaces to induce immune response UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2022-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11738096-B2 Method of detecting diseased or damaged tissue with a pH-triggered polypeptide fluorophore composition VIP, FUCA1, FGB KDM6B 4504/4885KDM4E 4881/4885HSD17B10 3315/4885
US-11267853-B2 Carbohydrate tethering at cell surfaces to induce immune response CD4, CD14, CD69 KDM6B 2650/4885KDM4E 3472/4885HSD17B10 2629/4885
US-20220088208-A1 PHLIP®-MEDIATED INTRACELLULAR DELIVERY OF IMMUNO-STIMULATORY COMPOUNDS STING1, MAVS, IRF3 KDM6B 3299/4885KDM4E 3697/4885HSD17B10 4472/4885
US-12397060-B2 pHLIP®-mediated intracellular delivery of immuno-stimulatory compounds STING1, MAVS, IRF3 KDM6B 3299/4885KDM4E 3697/4885HSD17B10 4472/4885
US-12290575-B2 Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide NPPA, LNPEP, VIP KDM6B 4491/4885KDM4E 4877/4885HSD17B10 3261/4885
US-11723897-B2 Fatty acids as anti-inflammatory agents ALOX15B, FFAR1, ALOX12 KDM6B 2503/4885KDM4E 2120/4885HSD17B10 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.